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    The DDBJ/EMBL/GenBank
    Feature Table:
    Definition

    Version 8  Oct 2008

    DNA Data Bank of Japan, Mishima, Japan.
    EMBL Nucleotide Sequence Database, Cambridge, UK.
    GenBank, NCBI, Bethesda, MD, USA.

    1 Introduction
    2 Overview of the Feature Table format
    2.1 Format Design
    2.2 Key aspects of this feature table design
    2.3 Feature Table Terminology
    3 Feature table components and format
    3.1 Naming conventions
    3.2 Feature keys
    3.2.1 Purpose
    3.2.2 Format and conventions
    3.2.3 Key groups and hierarchy
    3.2.4 Feature key examples
    3.3 Qualifiers
    3.3.1 Purpose
    3.3.2 Format and conventions
    3.3.3 Qualifier values
    3.3.4 Qualifier examples
    3.4 Feature labels
    3.4.1 Purpose
    3.4.2 Format and conventions
    3.4.3 Examples of feature labels
    3.5 Location
    3.5.1 Purpose
    3.5.2 Format and conventions
    3.5.3 Location examples
    4 Feature table Format
    4.1 Format examples
    4.2 Definition of line types
    4.3 Data item positions
    4.4 Use of blanks
    5 Examples of sequence annotation
    5.1 Eukaryotic gene
    5.2 Bacterial operon
    5.3 Artificial cloning vector (circular)
    5.4 Plasmid
    5.5 Repeat element
    5.6 Immunoglobulin heavy chain
    5.7 T-cell receptor
    5.8 Transfer RNA
    6 Limitations of this feature table design
    7 Appendices
    7.1 Appendix I EMBL, GenBank and DDBJ entries
    7.1.1 EMBL Format
    7.1.2 GenBank Format
    7.1.3 DDBJ Format
    7.2 Appendix II Feature table: Backus-Naur form
    7.3 Appendix III: Feature keys reference
    7.4 Appendix IV: Summary of qualifiers for feature keys
    7.4.1 Qualifier List
    7.4.2 Feature qualifiers - mapped to Feature keys
    7.5 Appendix V: Controlled vocabularies
    7.5.1 Nucleotide base codes (IUPAC)
    7.5.2 Modified base abbreviations
    7.5.3 Amino acid abbreviations
    7.5.4 Modified and unusual Amino Acids
    7.5.5 Genetic Code Tables
    7.5.6 Country Names

    1 Introduction

    Nucleic acid sequences provide the fundamental starting point for describing
    and understanding the structure, function, and development of genetically
    diverse organisms. The GenBank, EMBL, and DDBJ nucleic acid sequence data
    banks have from their inception used tables of sites and features to describe
    the roles and locations of higher order sequence domains and elements within
    the genome of an organism.
    In February, 1986, GenBank and EMBL began a collaborative effort (joined by
    DDBJ in 1987) to devise a common feature table format and common standards for
    annotation practice.

    2 Overview of the Feature Table format

    The overall goal of the feature table design is to provide an extensive
    vocabulary for describing features in a flexible framework for manipulating
    them. The Feature Table documentation represents the shared rules that allow
    the three databases to exchange data on a daily basis.
    The range of features to be represented is diverse, including regions which:
    * perform a biological function,
    * affect or are the result of the expression of a biological function,
    * interact with other molecules,
    * affect replication of a sequence,
    * affect or are the result of recombination of different sequences,
    * are a recognizable repeated unit,
    * have secondary or tertiary structure,
    * exhibit variation, or have been revised or corrected.

    2.1 Format Design

    The format design is based on a tabular approach and consists of the following
    items:

    Feature key - a single word or abbreviation indicating functional group
    Location - instructions for finding the feature
    Qualifiers - auxiliary information about a feature

    2.2 Key aspects of this feature table design

    * Feature keys allow specific annotation of important sequence features.

    * Related features can be easily specified and retrieved.
    Feature keys are arranged hierarchically, allowing complex and compound
    features to be expressed. Both location operators and the feature keys show
    feature relationships even when the features are not contiguous. The hierarchy
    of feature keys allows broad categories of biological functionality, such as
    rRNAs, to be easily retrieved.

    * Generic feature keys provide a means for entering new or undefined features.
    A number of "generic" or miscellaneous feature keys have been added to permit
    annotation of features that cannot be adequately described by existing feature
    keys. These generic feature keys will serve as an intermediate step in the
    identification and addition of new feature keys. The syntax has been designed
    to allow the addition of new feature keys as they are required.

    * More complex locations (fuzzy and alternate ends, for example) can be specified.
    Each end point of a feature may be specified as a single point, an alternate
    set of possible end points, a base number beyond which the end point lies, or
    a region which contains the end point.

    * Features can be combined and manipulated in many different ways.
    The location field can contain operators or functional descriptors specifying
    what must be done to the sequence to reproduce the feature. For example, a
    series of exons may be "join"ed into a full coding sequence.

    * Standardized qualifiers provide precision and parsibility of descriptive details
    A combination of standardized qualifiers and their controlled-vocabulary
    values enable free-text descriptions to be avoided.

    * The nature of supporting evidence for a feature can be explicitly indicated.
    Features, such as open reading frames or sequences showing sequence similarity
    to consensus sequences, for which there is no direct experimental evidence can
    be annotated. Therefore, the feature table can incorporate contributions from
    researchers doing computational analysis of the sequence databases. However,
    all features that are supported by experimental data will be clearly marked as
    such.

    * The table syntax has been designed to be machine parsible.
    A consistent syntax allows machine extraction and manipulation of sequences
    coding for all features in the table.

    2.3 Feature Table Terminology
    The format and wording in the feature table use common biological research
    terminology whenever possible. For example, an item in the feature table such as:

    Key             Location/Qualifiers
    CDS             23..400
                    /product="alcohol dehydrogenase"
                    /gene="adhI"

    might be read as:
    The feature  CDS  is a coding sequence beginning at base 23 and ending at base
    400, has a product called 'alcohol dehydrogenase' and is coded for by a gene
    called "adhI".

    A more complex description:
    Key             Location/Qualifiers
    CDS             join(544..589,688..>1032)
                    /product="T-cell receptor beta-chain"

    which might be read as:
    This feature, which is a partial coding sequence,  is formed by joining
    elements indicated to form one contiguous sequence encoding a product called T-
    cell receptor beta-chain.

    The following sections contain detailed explanations of the feature table
    design showing conventions for each component of the feature table, examples
    of how the format might be implemented, a description of the exact column
    placement of all the data items and examples of complete sequence entries that
    have been annotated using the new format. The last section of this document
    describes known limitations of the current feature table design.

    Appendix I gives an example database entry for the DDBJ, GenBank  and EMBL
    formats.

    Appendix II describes the format in Backus-Naur Form (BNF). This information
    will not be presented in future editions of this document.

    Appendices III and IV provide reference manuals for the feature table keys and
    qualifiers, respectively.

    Appendix V includes controlled vocabularies such as nucleotide base codes,
    modified base abbreviations, genetic code tables etc.

    This document defines the syntax and vocabulary of the feature table. The
    syntax is sufficiently flexible to allow expression of a single biological
    entity in numerous ways. In such cases, the annotation staffs at the databases
    will propose conventions for standard means of denoting the entities.
    This feature table format is shared by GenBank, EMBL and DDBJ. Comments,
    corrections, and suggestions may be submitted to any of the database staffs.
    New format specifications will be added as needed.

    3 Feature table components and format
    3.1 Naming conventions

    Feature table components, including feature keys, qualifiers, accession
    numbers, database name abbreviations, feature labels, and location operators,
    are all named following the same conventions. Component names may be no more
    than 20 characters long  (Feature keys 15, Feature qualifiers 20) and must
    contain at least one letter. Case should not be regarded as significant in
    comparing feature labels ("Prot1" and "pROT1" are the same). The following
    characters are permitted to occur in feature table component names:

    * Uppercase letters (A-Z)
    * Lowercase letters (a-z) Numbers (0-9)
    * Underscore (_)
    * Hyphen (-)
    * Single quotation mark or apostrophe (')
    * Asterisk (*)

    3.2 Feature keys
    3.2.1 Purpose

    Feature keys indicate
    (1) the biological nature of the annotated feature or
    (2) information about changes to or other versions of the sequence.
    The feature key permits a user to quickly find or retrieve similar features or
    features with related functions.

    3.2.2 Format and conventions

    There is a defined list of allowable feature keys, which is shown in Appendix
    III. Each feature must contain a feature key.

    3.2.3 Key groups and hierarchy

    The feature keys fall into families which are in some sense similar in
    function and which are annotated in a similar manner. A functional family may
    have a "generic" or miscellaneous key, which can be recognized by the 'misc.'
    prefix, that can used for instances not covered by the other defined keys of
    that group.

    The feature key groups are listed below with a short definition and an
    annotation example:

    1. Difference and change features
    Indicate ways in which a sequence should be changed to produce a different
    "version":
    misc_difference location
                  /replace="change_location"

    2. Expression signal features
    Indicate regions containing a signal that alters a biological function:
    misc_signal     location

    3. Transcript features
     Indicate products made by a region:
    misc_RNA        location

    4. Binding features
    Indicate that a sequence or nucleotide is covalently, non-covalently, or
    otherwise bound to something else:
    misc_binding    location
                  /bound_moiety="bound molecule"

    5. Repeat features
    Indicate repetitive sequence elements:
    repeat_region   location

    6. Recombination features
    Indicate regions that have been either inserted or deleted by recombination:
    misc_recomb     location

    7. Structure features
    Indicate sequence for which there is secondary or tertiary structural
    information:
    misc_structure  location

    In addition to the functional groupings shown above, the feature keys can also
    be arranged in a hierarchical tree based on the degree of specificity or level
    of detail known about a feature. This hierarchy is shown in outline form in
    Appendix III where the most general level is the 'misc_feature' key and other
    keys are arranged in increasing level of detail. By using more general keys,
    features can be annotated even if their biological functions are
    insufficiently well characterized to assign them more specific keys.

    3.2.4 Feature key examples

    Key                     Description

    CDS                     Protein-coding sequence
    RBS                     ribosome binding site
    rep_origin              Origin of replication
    protein_bind            Protein binding site on DNA
    tRNA                    mature transfer RNA

    See Appendix III for descriptions of all feature keys.

    3.3 Qualifiers

    3.3.1 Purpose

    Qualifiers provide a general mechanism for supplying information about
    features in addition to that conveyed by the key and location.

    3.3.2 Format and conventions

    Qualifiers take the form of a slash (/) followed by the qualifier name and, if
    applicable, an equal sign (=) and a value. Each qualifier should have a single
    value; if multiple values are necessary, these should be represented by
    iterating the same qualifier, eg:
    Key             Location/Qualifiers

    CDS             1..1000
                    /codon=(seq:"cug",aa:Ser)
                    /codon=(seq:"tga",aa:Trp)

    If the location descriptor does not need a continuation line, the first
    qualifier begins a new line in the feature location column. If the location
    descriptor requires a continuation line, the first qualifier may follow
    immediately after the location. Any necessary continuation lines begin in the
    same column. See Section 4 for a complete description of data item positions.

    3.3.3 Qualifier values

    Since qualifiers convey many different types of information, there are several value formats:
    1. Free text
    2. Controlled vocabulary or enumerated values
    3. Citation or reference numbers
    4. Sequences
    5. Feature labels

    3.3.3.1 Free text

    Most qualifier values will be a descriptive text phrase which must be enclosed
    in double quotation marks. When the text occupies more than one line, a single
    set of quotation marks is required at the beginning and at the end of the
    text. The text itself may be composed of any printable characters (ASCII
    values 32-126 decimal). If double quotation marks are used within a free text
    string, each set (") must be 'escaped' by placing a second double quotation
    mark immediately before it (""). For example:
                  /note="This is an example of ""escaped"" quotation marks"

    3.3.3.2 Controlled vocabulary or enumerated values

    Some qualifiers require values from a controlled vocabulary and are entered
    without quotation marks. For example, the '/direction' qualifier has only
    three values: 'left', 'right' or 'both'. Qualifier value controlled
    vocabularies, like feature table component names, must be treated as
    completely case insensitive: they may be entered and displayed in any
    combination of upper and lower case ('/direction=Left' '/direction=left' and '/
    direction=LEFT' are all legal and all convey the same meaning). The database
    staffs reserve the right to regularize the case of qualifier values in the
    interest of readability, unlike the case of feature labels where the databases
    will maintain the case as originally entered (see Section 3.4.2). Qualifier
    value controlled vocabularies will be maintained by the cooperating database
    staffs. Examples of controlled vocabularies can be found in Appendices IV and
    V. The database staff should be contacted for the current lists.

    3.3.3.3 Citation or reference numbers

    The citation or published reference number (as enumerated in the entry
    'REFERENCE' or 'RN' data item) should be enclosed in square brackets
    (e.g., [3]) to distinguish it from other numbers.

    3.3.3.4 Sequences

    Literal sequence of nucleotide bases e.g., join(12..45,"atgcatt",988..1050) in
    location descriptors has become illegal starting from implementation of
    version 2.1 of the Feature Table Definition Document (December 15, 1998)

    3.3.4 Qualifier examples

    Key             Location/Qualifiers

    source          1..1509
                    /organism="Mus musculus"
                    /strain="CD1"
                    /mol_type="genomic DNA"
    promoter        <1..9
                    /gene="ubc42"
    mRNA            join(10..567,789..1320)
                    /gene="ubc42"
    CDS             join(54..567,789..1254)
                    /gene="ubc42"
                    /product="ubiquitin conjugating enzyme"
                    /function="cell division control"

    3.4 Feature labels

    The /label= qualifier takes as its value a feature label. Feature labels
    follow the same naming conventions as other feature table components (e.g.,
    keys and qualifiers). While feature labels are optional, attaching a label to
    a feature allows it to be referred to unambiguously. For example, the feature
    label can be used to refer unambiguously to a coding region that exists in a
    different entry to the exons of which it is comprised.

    3.4.1 Purpose

    The feature label identifies a feature item within an entry and, when combined
    with the entry's primary accession number and the name of the database from
    which it came, is a permanent internationally unique tag for that feature.
    There are, however, certain situations in which a "permanent" feature may "
    disappear" from the distributed version of the database and others in which it
    may be desirable to change a feature's label.

    3.4.2 Format and conventions

    Each feature in a feature table may have a label which must be unique within
    that entry, but which may be the same as feature labels used in other entries.
    A feature can be given any label. However, labels containing meaningful
    abbreviations will be much more easily remembered than non-descriptive labels.
    Because letter case is not significant, two features within one entry cannot
    have labels that differ only in case: '16S_rRNA' and '16s_rRNA' could not both
    be used in the same entry.
    The full feature name syntax is as follows:
              Database name::primary accession number:feature label
    References to a feature should use as much of the full feature name as
    required to unambiguously identify the feature.

    3.4.3 Examples of feature labels

    Feature label           Description

    adhI                    adhI gene coding for alcohol dehydrogenase
    tfp35                   tail fiber protein 35
    3'-ltr                  long terminal repeat
    a1col_x51               prepro-alpha-1-collagen, exon 51
    X10045:diff1            first conflict for the sequence of entry X10045
    GB::K10675:catexA       feature with label catexA in entry K10675 of the
                            GenBank databank

    3.5 Location
    3.5.1 Purpose

    The location indicates the region of the presented sequence which corresponds
    to a feature.

    3.5.2 Format and conventions
    The location contains at least one sequence location descriptor and may
    contain one or more operators with one or more sequence location descriptors.
    Base numbers refer to the numbering in the entry. This numbering designates
    the first base (5' end) of the presented sequence as base 1.
    Base locations beyond the range of the presented sequence may not be used in
    location descriptors, the only exception being location in a remote entry (see
    3.5.2.1, e).

    Location operators and descriptors are discussed in more detail below.

     3.5.2.1 Location descriptors
    The location descriptor can be one of the following:
    (a) a single base number
    (b) a site between two indicated adjoining bases
    (c) a single base chosen from within a specified range of bases (not allowed for new
        entries)
    (d) the base numbers delimiting a sequence span
    (e) a remote entry identifier followed by a local location descriptor
        (i.e., a-d)

    A site between two adjoining nucleotides, such as endonucleolytic cleavage
    site, is indicated by listing the two points separated by a carat (^). The
    permitted formats for this descriptor are n^n+1 (for example 55^56), or, for
    circular molecules, n^1, where "n" is the full length of the molecule, ie
    1000^1 for circular molecule with length 1000.

    A single base chosen from a range of bases is indicated by the first base
    number and the last base number of the range separated by a single period
    (e.g., '12.21' indicates a single base taken from between the indicated
    points). From October 2006 the usage of this descriptor is restricted :
    it is illegal to use "a single base from a range" (c) either on its own or
    in combination with the "sequence span" (d) descriptor for newly created entries.
    The existing entries where such descriptors exist are going to be retrofitted.

    Sequence spans are indicated by the starting base number and the ending base
    number separated by two periods (e.g., '34..456'). The '<' and '>' symbols may
    be used with the starting and ending base numbers to indicate that an end
    point is beyond the specified base number. The starting and ending base
    positions can be represented as distinct base numbers ('34..456') or a site
    between two indicated adjoining bases.

    A location in a remote entry (not the entry to which the feature table
    belongs) can be specified by giving  the accession-number and sequence version
    of the remote entry, followed by a colon ":", followed by a location
    descriptor which applies to that entry's sequence (i.e. J12345.1:1..15, see
    also examples below)

    3.5.2.2 Operators

    The location operator is a prefix that specifies what must be done to the
    indicated sequence to find or construct the location corresponding to the
    feature. A list of operators is given below with their definitions and most
    common format.

    complement(location)
    Find the complement of the presented sequence in the span specified by "
    location" (i.e., read the complement of the presented strand in its 5'-to-3'
    direction)

    join(location,location, ... location)
    The indicated elements should be joined (placed end-to-end) to form one
    contiguous sequence

    order(location,location, ... location)
    The elements can be found in the
    specified order (5' to 3' direction), but nothing is implied about the
    reasonableness about joining them

    Note : location operator "complement" can be used in combination with either "
    join" or "order" within the same location; combinations of "join" and "order"
    within the same location (nested operators) are illegal.

    3.5.3 Location examples

    The following is a list of common location descriptors with their meanings:

    Location                  Description

    467                       Points to a single base in the presented sequence

    340..565                  Points to a continuous range of bases bounded by and
                              including the starting and ending bases

    <345..500                 Indicates that the exact lower boundary point of a feature
                              is unknown.  The location begins at some  base previous to
                              the first base specified (which need not be contained in
                              the presented sequence) and continues to and includes the
                              ending base

    <1..888                   The feature starts before the first sequenced base and
                              continues to and includes base 888

    1..>888                   The feature starts at the first sequenced base and
                              continues beyond base 888

    102.110                   Indicates that the exact location is unknown but that it is
                              one of the bases between bases 102 and 110, inclusive

    123^124                   Points to a site between bases 123 and 124

    join(12..78,134..202)     Regions 12 to 78 and 134 to 202 should be joined to form
                              one contiguous sequence

    complement(34..126)       Start at the base complementary to 126 and finish at the
                              base complementary to base 34 (the feature is on the strand
                              complementary to the presented strand)

    complement(join(2691..4571,4918..5163))
                              Joins regions 2691 to 4571 and 4918 to 5163, then
                              complements the joined segments (the feature is on the
                              strand complementary to the presented strand)

    join(complement(4918..5163),complement(2691..4571))
                              Complements regions 4918 to 5163 and 2691 to 4571, then
                              joins the complemented segments (the feature is on the
                              strand complementary to the presented strand)

    J00194.1:100..202         Points to bases 100 to 202, inclusive, in the entry (in
                              this database) with primary accession number 'J00194'

    join(1..100,J00194.1:100..202)
                              Joins region 1..100 of the existing entry with the region
                              100..202 of remote entry J00194

    4 Feature table Format

    The examples below show the preferred sequence annotations for a number of
    commonly occurring sequence types. These examples may not be appropriate in
    all cases but should be used as a guide whenever possible. This section
    describes the columnar format used to write this feature table in "flat-file"
    form for distributions of the database.

    4.1 Format examples

    Feature table format example (EMBL):
         source          1..1859
                         /db_xref="taxon:3899"
                         /organism="Trifolium repens"
                         /tissue_type="leaves"
                         /clone_lib="lambda gt10"
                         /clone="TRE361"
                         /mol_type="genomic DNA"
         CDS             14..1495
                         /db_xref="MENDEL:11000"
                         /db_xref="SWISS-PROT:P26204"
                         /note="non-cyanogenic"
                         /EC_number="3.2.1.21"
                         /product="beta-glucosidase"
                         /protein_id="CAA40058.1"
                         /translation="MDFIVAIFALFVISSFTITSTNAVEASTLLDIGNLSR.......
    ---------+---------+---------+---------+---------+---------+---------+---------
    1       10        20        30        40        50        60        70       79

    Feature table format example (GenBank):

         source          1..8959
                         /organism="Homo sapiens"
                         /db_xref="taxon:9606"
                         /mol_type="genomic DNA"
         gene            212..8668
                         /gene="NF1"
         CDS             212..8668
                         /gene="NF1"
                         /note="putative"
                         /codon_start=1
                         /product="GAP-related protein"
                         /protein_id="AAA59924.1"
                         /translation="MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTE.......
    ---------+---------+---------+---------+---------+---------+---------+---------
    1       10        20        30        40        50        60        70       79

    Feature table format example (DDBJ):

         source          1..2136
                         /clone="pK28"
                         /organism="Rattus norvegicus"
                         /strain="Sprague-Dawley"
                         /tissue_type="kidney"
                         /mol_type="genomic DNA"
         mRNA            19..2128
         CDS             31..1212
                         /codon_start=1
                         /function="Dual specificity protein tyrosine/threonine
                         kinase"
                         /product="MAP kinase kinase"
                         /protein_id="BAA02603.1"
                         /translation="MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKL.......
    ---------+---------+---------+---------+---------+---------+---------+---------
    1       10        20        30        40        50        60        70       79

    4.2 Definition of line types
    The feature table consists of a header line, which contains the column titles
    for the table, and the individual feature entries. Each feature entry is
    composed of a feature descriptor line and qualifier and continuation lines,
    if needed. The feature descriptor line contains the feature's name, key, and
    location. If the location cannot be contained on the first line of the feature
    descriptor, it is continued on a continuation line immediately following the
    descriptor line. If the feature requires further attributes, feature qualifier
    lines immediately follow the corresponding feature descriptor line (or its
    continuation). Qualifier information that cannot be contained on one line
    continues on the following continuation lines as necessary.

    Thus, there are 4 types of feature table lines:
          Line type            Content                 #/entry     #/feature
          ---------            -------                 -------     ---------

          Header               Column titles           1*          N/A
          Feature descriptor   Key and location        1 to many*  1
          Feature qualifiers   Qualifiers and values   N/A         0 to many
          Continuation lines   Feature descriptor or   0 to many   0 to many
                               qualifier continuation

    4.3 Data item positions

    The position of the data items within the feature descriptor line is as follows:
         column position    data item
         ---------------    ---------

         1-5                blank
         6-20               feature key
         21                 blank
         22-80              location

    Data on the qualifier and continuation lines begins in column position 22 (the
    first 21 columns contain blanks). The EMBL format for all lines differs from
    the GenBank / DDBJ formats  that it includes a line type abbreviation in
    columns 1 and 2.

    4.4 Use of blanks

    Blanks (spaces) may, in general, be used within the feature location and
    qualifier values to make the construction more readable. The following rules
    should be observed:
    * Names of feature table components may not contain blanks (see Section 3.1)
    * Operator names may not be separated from the following open parenthesis (the
      beginning of the operand list) by blanks.
    * Qualifiers may not be separated from the preceding slash or the following
      equals sign (if one) by blanks

    5 Examples of sequence annotation

    The examples below show the preferred sequence annotations for a number of
    commonly occurring sequence types. These examples may not be appropriate in
    all cases but should be used as a guide whenever possible.

    5.1 Eukaryotic gene

    source             1..1509
                       /organism="Mus musculus"
                       /strain="CD1"
                       /mol_type="genomic DNA"
    promoter           <1..9
                       /gene="ubc42"
    mRNA               join(10..567,789..1320)
                       /gene="ubc42"
    CDS                join(54..567,789..1254)
                       /gene="ubc42"
                       /product="ubiquitin conjugating enzyme"
                       /function="cell division control"
                       /translation="MVSSFLLAEYKNLIVNPSEHFKISVNEDNLTEGPPDTLY
                       QKIDTVLLSVISLLNEPNPDSPANVDAAKSYRKYLYKEDLESYPMEKSLDECS
                       AEDIEYFKNVPVNVLPVPSDDYEDEEMEDGTYILTYDDEDEEEDEEMDDE"
    exon               10..567
                       /gene="ubc42"
                       /number=1
    intron             568..788
                       /gene="ubc42"
                       /number=1
    exon               789..1320
                       /gene="ubc42"
                       /number=2
    polyA_signal       1310..1317
                       /gene="ubc42"

    5.2 Bacterial operon

    source                  1..9430
                            /organism="Lactococcus sp."
                            /strain="MG1234"
                            /mol_type="genomic DNA"
    operon                  160..6865
                            /operon="gal"
    -35_signal              160..165
                            /operon="gal"
                            /experiment="experimental evidence, no additional details
                            recorded"
    -10_signal              179..184
                            /operon="gal"
                            /experiment="experimental evidence, no additional details
                            recorded"
    CDS                     405..1934
                            /operon="gal"
                            /gene="galA"
                            /product="galactose permease"
                            /function="galactose transporter"
                            /experiment="experimental evidence, no additional details
                            recorded"
    CDS                     2003..3001
                            /operon="gal"
                            /gene="galM"
                            /product="aldose 1-epimerase"
                            /EC_number="5.1.3.3"
                            /function="mutarotase"
    CDS                     3235..4537
                            /operon="gal"
                            /gene="galK"
                            /product="galactokinase"
                            /EC_number="2.7.1.6"
                            /experiment="experimental evidence, no additional details
                            recorded"
    mRNA                    189..6865
                            /operon="gal"
                            /experiment="experimental evidence, no additional details
                            recorded"

    5.3 Artificial cloning vector (circular)

    source                  1..5300
                            /organism="Cloning vector pABC"
                            /lab_host="Escherichia coli"
                            /mol_type="other DNA"
                            /focus
    source                  1..5138
                            /organism="Escherichia coli"
                            /mol_type="other DNA"
                            /strain="K12"
    source                  5139..5247
                            /organism="Aequorea victoria"
                            /mol_type="other DNA"
                            /dev_stage="adult"
    source                  5248..5300
                            /organism="Escherichia coli"
                            /mol_type="other DNA"
                            /strain="K12"
    CDS                     join(complement(<1..799),complement(5080..5120))
                            /gene="mob1"
                            /product="mobilization protein 1"
    CDS                     complement(1697..2512)
                            /gene="Km"
                            /product="kanamycin resistance protein"
    CDS                     3037..3711
                            /gene="rep1"
                            /product="replication protein 1"
    CDS                     complement(4170..4829)
                            /gene="Cm"
                            /product="chloramphenicol resistance protein"
    CDS                     5139..5247
                            /gene="GFP"
                            /product="green fluorescent protein"

    5.4 Plasmid 5.4 Plasmid

    source                  1..2245
                            /organism="Escherichia coli"
                            /plasmid="Plasmid XYZ"
                            /strain="K12"
                            /mol_type="genomic DNA"
    rep_origin              6
                            /direction=LEFT
                            /note="ori"
    CDS                     join(complement(567..795),complement(21..349))
                            /gene="trbC"
                            /product="transfer protein C"
    CDS                     803..1344
                            /gene="traN"
                            /product="transfer protein N"
    CDS                     1559..1985
                            /gene="incA"
                            /product="incompatability protein A"
    CDS                     join(2004..2195,3..20)
                            /gene="finP"
                            /product="fertility inhibition protein P"
    5.5 Repeat element

    source                  1..1011
                            /organism="Homo sapiens"
                            /clone="pha281u/1DO"
                            /mol_type="genomic DNA"
    repeat_region           80..401
                            /rpt_type=DISPERSED
                            /rpt_family="Alu-J"

    5.6 Immunoglobulin heavy chain

    source                  1..321
                            /organism="Mus musculus "
                            /strain="BALB/c2
                            /cell_line="hybridoma 1A4"
                            /rearranged
                            /mol_type="mRNA"
    CDS                     <1..>321
                            /codon_start=1
                            /gene="VFM1-DFL16.1-JH4"
                            /product="immunoglobulin heavy chain"
    V_region                1..277
                            /gene="VFM1"
                            /product="immunoglobulin heavy chain variable region"

    5.7 T-cell receptor

    source                  1..402
                            /organism="Homo sapiens"
                            /sex="male"
                            /cell_type="CD4+ T-lymphocyte"
                            /rearranged
                            /clone="TCR1A.12"
                            /mol_type="mRNA"
    sig_peptide             1..54
                            /gene="TCR1A"
    CDS                     1..402
                            /gene="TCR1A"
                            /product="T-cell receptor alpha chain"
    mat_peptide             55..399
                            /gene="TCR1A"
                            /product="T-cell receptor alpha chain"
    V_region                55..327
                            /gene="TCR1A"
    J_segment               328..393
                            /gene="TCR1A"
    C_region                394..399
                            /gene="TCR1A"

    5.8 Transfer RNA

    source          1..2345
                    /organism="Yersinia sp."
                    /strain="IP134"
                    /mol_type="genomic DNA"
    -35_signal      644..650
                    /gene="tRNA-Leu(UUR)"
    tRNA            655..730
                    /gene="tRNA-Leu(UUR)"
                    /anticodon=(pos:678..680,aa:Leu)
                    /product="transfer RNA-Leu(UUR)"

    6. Limitations of this feature table design

    During the development of the feature table design numerous choices between
    simplicity and representational power had to be made. In order to create a
    design which was capable of representing the most common features of
    biological significance, a certain degree of complexity in the syntax was
    guaranteed. However, to limit that level of complexity, certain limitations of
    the design syntax have been accepted.

    7. Appendices

    7.1 Appendix I EMBL, GenBank and DDBJ entries

    7.1.1 EMBL Format

    ID   X64011; SV 1; linear; genomic DNA; STD; PRO; 756 BP.
    XX
    AC   X64011; S78972;
    XX
    SV   X64011.1
    XX
    DT   28-APR-1992 (Rel. 31, Created)
    DT   30-JUN-1993 (Rel. 36, Last updated, Version 6)
    XX
    DE   Listeria ivanovii sod gene for superoxide dismutase
    XX
    KW   sod gene; superoxide dismutase.
    XX
    OS   Listeria ivanovii
    OC   Bacteria; Firmicutes; Bacillus/Clostridium group;
    OC   Bacillus/Staphylococcus group; Listeria.
    XX
    RN   [1]
    RX   MEDLINE; 92140371.
    RA   Haas A., Goebel W.;
    RT   "Cloning of a superoxide dismutase gene from Listeria ivanovii by
    RT   functional complementation in Escherichia coli and characterization of the
    RT   gene product.";
    RL   Mol. Gen. Genet. 231:313-322(1992).
    XX
    RN   [2]
    RP   1-756
    RA   Kreft J.;
    RT   ;
    RL   Submitted (21-APR-1992) to the EMBL/GenBank/DDBJ databases.
    RL   J. Kreft, Institut f. Mikrobiologie, Universitaet Wuerzburg, Biozentrum Am
    RL   Hubland, 8700 Wuerzburg, FRG
    XX
    FH   Key             Location/Qualifiers
    FH
    FT   source          1..756
    FT                   /db_xref="taxon:1638"
    FT                   /organism="Listeria ivanovii"
    FT                   /strain="ATCC 19119"
    FT                   /mol_type="genomic DNA"
    FT   RBS             95..100
    FT                   /gene="sod"
    FT   terminator      723..746
    FT                   /gene="sod"
    FT   CDS             109..717
    FT                   /db_xref="SWISS-PROT:P28763"
    FT                   /transl_table=11
    FT                   /gene="sod"
    FT                   /EC_number="1.15.1.1"
    FT                   /db_xref="GOA:P28763"
    FT                   /db_xref="HSSP:P00448"
    FT                   /db_xref="InterPro:IPR001189"
    FT                   /db_xref="UniProtKB/Swiss-Prot:P28763"
    FT                   /product="superoxide dismutase"
    FT                   /protein_id="CAA45406.1"
    FT                   /translation="MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNIYVTKLNEAVSG
    FT                   HAELASKPGEELVANLDSVPEEIRGAVRNHGGGHANHTLFWSSLSPNGGGAPTGNLKAA
    FT                   IESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNNGKLEIVSTANQDSPLSEGKTPVLGL
    FT                   DVWEHAYYLKFQNRRPEYIDTFWNVINWDERNKRFDAAK"
    XX
    SQ   Sequence 756 BP; 247 A; 136 C; 151 G; 222 T; 0 other;
         cgttatttaa ggtgttacat agttctatgg aaatagggtc tatacctttc gccttacaat   60
         gtaatttctt ..........                                               120
    //

    7.1.2 GenBank Format

    LOCUS       LISOD                    756 bp    DNA     linear   BCT 30-JUN-1993
    DEFINITION  Listeria ivanovii sod gene for superoxide dismutase.
    ACCESSION   X64011 S78972
    VERSION     X64011.1  GI:44010
    KEYWORDS    sod gene; superoxide dismutase.
    SOURCE      Listeria ivanovii
      ORGANISM  Listeria ivanovii
                Bacteria; Firmicutes; Bacillales; Listeriaceae; Listeria.
    REFERENCE   1  (bases 1 to 756)
      AUTHORS   Haas,A. and Goebel,W.
      TITLE     Cloning of a superoxide dismutase gene from Listeria ivanovii by
                functional complementation in Escherichia coli and characterization
                of the gene product
      JOURNAL   Mol. Gen. Genet. 231 (2), 313-322 (1992)
      MEDLINE   92140371
    REFERENCE   2  (bases 1 to 756)
      AUTHORS   Kreft,J.
      TITLE     Direct Submission
      JOURNAL   Submitted (21-APR-1992) J. Kreft, Institut f. Mikrobiologie,
                Universitaet Wuerzburg, Biozentrum Am Hubland, 8700 Wuerzburg, FRG
    FEATURES             Location/Qualifiers
         source          1..756
                         /organism="Listeria ivanovii"
                         /strain="ATCC 19119"
                         /db_xref="taxon:1638"
                         /mol_type="genomic DNA"
         RBS             95..100
                         /gene="sod"
         gene            95..746
                         /gene="sod"
         CDS             109..717
                         /gene="sod"
                         /EC_number="1.15.1.1"
                         /codon_start=1
                         /transl_table=11
                         /product="superoxide dismutase"
                         /db_xref="GI:44011"
                         /db_xref="GOA:P28763"
                         /db_xref="InterPro:IPR001189"
                         /db_xref="UniProtKB/Swiss-Prot:P28763"
                         /protein_id="CAA45406.1"
                         /translation="MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNIYVTKLNEAVS
                         GHAELASKPGEELVANLDSVPEEIRGAVRNHGGGHANHTLFWSSLSPNGGGAPTGNLK
                         AAIESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNNGKLEIVSTANQDSPLSEGKTPV
                         LGLDVWEHAYYLKFQNRRPEYIDTFWNVINWDERNKRFDAAK"
         terminator      723..746
                         /gene="sod"
    ORIGIN
            1 cgttatttaa ggtgttacat agttctatgg aaatagggtc tatacctttc gccttacaat
           61 gtaatttctt ..........
    //

    7.1.3 DDBJ Format

    LOCUS       LISOD                    756 bp    DNA     linear   BCT 30-JUN-1993
    DEFINITION  Listeria ivanovii sod gene for superoxide dismutase.
    ACCESSION   X64011 S78972
    VERSION     X64011.1  GI:44010
    KEYWORDS    sod gene; superoxide dismutase.
    SOURCE      Listeria ivanovii
      ORGANISM  Listeria ivanovii
                Bacteria; Firmicutes; Bacillales; Listeriaceae; Listeria.
    REFERENCE   1  (bases 1 to 756)
      AUTHORS   Haas,A. and Goebel,W.
      TITLE     Cloning of a superoxide dismutase gene from Listeria ivanovii by
                functional complementation in Escherichia coli and characterization
                of the gene product
      JOURNAL   Mol. Gen. Genet. 231 (2), 313-322 (1992)
      MEDLINE   92140371
    REFERENCE   2  (bases 1 to 756)
      AUTHORS   Kreft,J.
      TITLE     Direct Submission
      JOURNAL   Submitted (21-APR-1992) J. Kreft, Institut f. Mikrobiologie,
                Universitaet Wuerzburg, Biozentrum Am Hubland, 8700 Wuerzburg, FRG
    FEATURES             Location/Qualifiers
         source          1..756
                         /organism="Listeria ivanovii"
                         /strain="ATCC 19119"
                         /db_xref="taxon:1638"
                         /mol_type="genomic DNA"
         RBS             95..100
                         /gene="sod"
         gene            95..746
                         /gene="sod"
         CDS             109..717
                         /gene="sod"
                         /EC_number="1.15.1.1"
                         /codon_start=1
                         /transl_table=11
                         /product="superoxide dismutase"
                         /db_xref="GOA:P28763"
                         /db_xref="HSSP:P00448"
                         /db_xref="InterPro:IPR001189"
                         /db_xref="UniProtKB/Swiss-Prot:P28763"
                         /protein_id="CAA45406.1"
                         /db_xref="SWISS-PROT:P28763"
                         /translation="MTYELPKLPYTYDALEPNFDKETMEIHYTKHHNIYVTKLNEAVS
                         GHAELASKPGEELVANLDSVPEEIRGAVRNHGGGHANHTLFWSSLSPNGGGAPTGNLK
                         AAIESEFGTFDEFKEKFNAAAAARFGSGWAWLVVNNGKLEIVSTANQDSPLSEGKTPV
                         LGLDVWEHAYYLKFQNRRPEYIDTFWNVINWDERNKRFDAAK"
         terminator      723..746
                         /gene="sod"
    BASE COUNT          247 a          136 c          151 g          222 t
    ORIGIN
            1 cgttatttaa ggtgttacat agttctatgg aaatagggtc tatacctttc gccttacaat
           61 gtaatttctt ..........
    //

    7.2 Appendix II Feature table: Backus-Naur form

    This information will not be presented in future editions of this document.

    Feature table is a mandatory  part of an entry.  Full entry syntax is
    specified elsewhere.
    feature_table ::= <feature_table_header><feature_table_body> feature_table_header ::=
    FH Key Location/Qualifiers |

    FEATURES Location/Qualifiers

    feature_table_body ::= <feature> | <feature_table_body><feature>
    At least one feature is required.

    feature ::= <feature_key><feature_details>
    Key is required, location required, qualifier list optional

    feature_key ::= <symbol> | -
    feature_details ::= <location><qualifier_list> | <location>
    There exists a table of legal keys.

    location ::= <absolute_location> | <feature_name> |

    <functional_operator>(<location_list>)

    absolute_location ::= <local_location> | <path> : <local_location>

    path ::= <database> :: <primary_accession> | <primary_accession>

    feature_name ::= <path>:<feature_label> | <feature_label>

    feature_label :== <symbol>

    local_location ::= <base_position> | <between_position> | <base_range>

    location_list ::= <location> | <location_list>,<location>

    functional_operator ::= <symbol>

    base_position ::= <integer> | <low_base_bound> | <high_base_bound> |

    <two_base_bound>

    low_base_bound ::= > <integer>

    high_base_bound ::= < <integer>

    two_base_bound ::= <base_position>.<base_position>

    between_position ::= <base_position>^<base_position>

    base_range ::= <base_position>..<base_position>

    database  ::= <symbol>

    primary_accession ::= <symbol>

    sequence_character ::= a | b | c | d | g | h | k | m | n | r | s | t | u | v | w | y

    qualifier_list ::= <qualifier> | <qualifier_list><qualifier>

    qualifier ::= /<qualifier_name> | /<qualifier_name>=<value>

    qualifier_name ::= <symbol>

    value ::= <simple_value> | (<value_list>) | (<tagged_value_list>)

    simple_value ::= <integer> | <location> | <reference_number> | "<text_string>" |

    <symbol>

    value_list ::= <value> | <value_list>,<value>

    tagged_value_list ::= <tagged_value> | <tagged_value_list>,<tagged_value>

    tagged_value ::= <tag>:<value>

    tag ::= <symbol>

    reference_number ::= [ <unsigned_integer> ]

    symbol  ::= <letter> | <symbol><symbol_character> | <symbol_character><symbol>

    text_string ::= <string_character>| <text_string><string_character>

    unsigned_integer ::= <digit> |  <unsigned_integer><digit>

    integer ::= <unsigned_integer> | - <unsigned_integer>

    string_character ::= <letter> | <digit> | <punctuation> | ""

    symbol_character ::= <up_case_letter> | <low_case_letter> |<digit> | _ | - | ' | *

    letter ::= <up_case_letter> | <low_case_letter>

    up_case_letter ::= A | B| ... | Z

    low_case_letter ::= a | b | ... | z

    digit ::= 0 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9

    punctuation ::= <space> | ! | # | $ | % | & | ' | ( | ) | * | + | , |
     - | . | / | : | ; | < | = | > | ? | @ | [ | \ | ] | ^ | _ | ` | { |
     <bar> | } | ~

    bar ::= |

    space ::= ascii 32

    7.3 Appendix III: Feature keys reference

    The following has been organized according to the following format:
    Feature Key             the feature key name
    Definition              the definition of the key
    Mandatory qualifiers    qualifiers required with the key; if there are no
                            mandatory qualifiers, this field is omitted.
    Optional qualifiers     optional qualifiers associated with the key
    Organism scope          valid organisms for the key; if the scope is any
                            organism, this field is omitted.
    Molecule scope          valid molecule types; if the scope is any molecule
                            type, this field is omitted.
    References              citations of published reports, usually supporting the
                            feature consensus sequence
    Comment                 comments and clarifications
    Abbreviations:
    accnum                  an entry primary accession number
    <amino_acid>            abbreviation for amino acid
    <base_range>            location descriptor for a simple range of bases
    <bool>                  Boolean truth value.  Valid values are yes and no
    feature_label           the feature label (follows naming conventions for all
                            feature table components)
    <integer>               unsigned integer value
    <location>              general feature location descriptor
    <modified_base>         abbreviation for modified nucleotide base
    [number]                integer representing number of citation in entry's
                            reference list
    <repeat_type>           value indicating the organization of a repeated
                            sequence.
    "text"                  any text or character string. Since the string is
                            delimited by double quotes, double quotes may only
                            appear as part of the string if they appear in pairs.
                            For example, the sentence:

                            The feature label "ops-tata" is used with the
                            "promotor" feature key

                            would be formatted thus:

                            "The feature label""ops-tata" " is used with the
                            " "promoter" "  feature key"

    Feature Key           attenuator

    Definition            1) region of DNA at which regulation of termination of
                             transcription occurs, which controls the expression
                             of some bacterial operons;
                          2) sequence segment located between the promoter and the
                             first structural gene that causes partial termination
                             of transcription

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /phenotype="text"

    Organism scope        prokaryotes

    Molecule scope        DNA

    Feature Key           C_region

    Definition            constant region of immunoglobulin light and heavy
                          chains, and T-cell receptor alpha, beta, and gamma
                          chains; includes one or more exons depending on the
                          particular chain

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            CDS

    Organism scope        eukaryotes

    Feature Key           CAAT_signal

    Definition            CAAT box; part of a conserved sequence located about 75
                          bp up-stream of the start point of eukaryotic
                          transcription units which may be involved in RNA
                          polymerase binding; consensus=GG(C or T)CAATCT [1,2].

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Organism scope        eukaryotes and eukaryotic viruses

    Molecule scope        DNA

    References            [1]  Efstratiadis, A.  et al.  Cell 21, 653-668 (1980)
                          [2]  Nevins, J.R.  "The pathway of eukaryotic mRNA formation"
                               Ann Rev Biochem 52, 441-466 (1983)

    Feature Key           CDS

    Definition            coding sequence; sequence of nucleotides that
                          corresponds with the sequence of amino acids in a
                          protein (location includes stop codon);
                          feature includes amino acid conceptual translation.

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /codon=(seq:"codon-sequence",aa:<amino_acid>)
                          /codon_start=<1 or 2 or 3>
                          /db_xref="<database>:<identifier>"
                          /EC_number="text"
                          /exception="text"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /number=unquoted text (single token)
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /product="text"
                          /protein_id="<identifier>"
                          /pseudo
                          /ribosomal_slippage
                          /standard_name="text"
                          /translation="text"
                          /transl_except=(pos:<base_range>,aa:<amino_acid>)
                          /transl_table =<integer>
                          /trans_splicing

    Comment               /codon_start has valid value of 1 or 2 or 3, indicating
                          the offset at which the first complete codon of a coding
                          feature can be found, relative to the first base of
                          that feature;
                          /transl_table defines the genetic code table used if
                          other than the universal genetic code table;
                          genetic code exceptions outside the range of the specified
                          tables are reported in /codon or /transl_except qualifiers
                          /protein_id consists of a stable ID portion (3+5 format
                          with 3 position letters and 5 numbers) plus a version
                          number after the decimal point; when the protein
                          sequence encoded by the CDS changes, only the version
                          number of the /protein_id value is incremented; the
                          stable part of the /protein_id remains unchanged and as
                          a result will permanently be associated with a given
                          protein;

    Feature Key           conflict

    Definition            independent determinations of the "same" sequence differ
                          at this site or region;

    Mandatory qualifiers  /citation=[number]
                          Or
                          /compare=[accession-number.sequence-version]

    Optional qualifiers   /allele="text"
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /replace="text"

    Comment               use /replace="" to annotate deletion, e.g.
                          conflict    4..5
                                      /replace=""

    Feature Key           D-loop

    Definition            displacement loop; a region within mitochondrial DNA in
                          which a short stretch of RNA is paired with one strand
                          of DNA, displacing the original partner DNA strand in
                          this region; also used to describe the displacement of a
                          region of one strand of duplex DNA by a single stranded
                          invader in the reaction catalyzed by RecA protein

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Molecule scope        DNA

    Feature Key           D_segment

    Definition            Diversity segment of immunoglobulin heavy chain, and
                          T-cell receptor beta chain;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            CDS

    Organism scope        eukaryotes

    Feature Key           enhancer

    Definition            a cis-acting sequence that increases the utilization of
                          (some)  eukaryotic promoters, and can function in either
                          orientation and in any location (upstream or downstream)
                          relative to the promoter;

    Optional qualifiers   /allele="text"
                          /bound_moiety="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /label=feature_label
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Organism scope        eukaryotes and eukaryotic viruses

    Feature Key           exon

    Definition            region of genome that codes for portion of spliced mRNA,
                          rRNA and tRNA; may contain 5'UTR, all CDSs and 3' UTR;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /EC_number="text"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /number=unquoted text (single token)
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Feature Key           gap

    Definition            gap in the sequence
    Mandatory qualifiers  /estimated_length=unknown or <integer>
    Optional qualifiers   /experiment="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /map="text"
                          /note="text"
    Comment               the location span of the gap feature for an unknown
                          gap is 100 bp, with the 100 bp indicated as 100 "n"'s in
                          the sequence.  Where estimated length is indicated by
                          an integer, this is indicated by the same number of
                          "n"'s in the sequence.
                          No upper or lower limit is set on the size of the gap.

    Feature Key           GC_signal

    Definition            GC box; a conserved GC-rich region located upstream of
                          the start point of eukaryotic transcription units which
                          may occur in multiple copies or in either orientation;
                          consensus=GGGCGG;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Organism scope        eukaryotes and eukaryotic viruses

    Feature Key           gene

    Definition            region of biological interest identified as a gene
                          and for which a name has been assigned;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /product="text"
                          /pseudo
                          /phenotype="text"
                          /standard_name="text"
                          /trans_splicing

    Comment               the gene feature describes the interval of DNA that
                          corresponds to a genetic trait or phenotype; the feature is,
                          by definition, not strictly bound to it's positions at the
                          ends;  it is meant to represent a region where the gene is
                          located.

    Feature Key           iDNA

    Definition            intervening DNA; DNA which is eliminated through any of
                          several kinds of recombination;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /number=unquoted text (single token)
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Molecule scope        DNA

    Comment               e.g., in the somatic processing of immunoglobulin genes.

    Feature Key           intron

    Definition            a segment of DNA that is transcribed, but removed from
                          within the transcript by splicing together the sequences
                          (exons) on either side of it;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /number=unquoted text (single token)
                          /old_locus_tag="text" (single token)
                          /pseudo
                          /standard_name="text"

    Feature Key           J_segment

    Definition            joining segment of immunoglobulin light and heavy
                          chains, and T-cell receptor alpha, beta, and gamma
                          chains;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            CDS

    Organism scope        eukaryotes

    Feature Key           LTR

    Definition            long terminal repeat, a sequence directly repeated at
                          both ends of a defined sequence, of the sort typically
                          found in retroviruses;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Feature Key           mat_peptide

    Definition            mature peptide or protein coding sequence; coding
                          sequence for the mature or final peptide or protein
                          product following post-translational modification; the
                          location does not include the stop codon (unlike the
                          corresponding CDS);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /EC_number="text"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Feature Key           misc_binding

    Definition            site in nucleic acid which covalently or non-covalently
                          binds another moiety that cannot be described by any
                          other binding key (primer_bind or protein_bind);

    Mandatory qualifiers  /bound_moiety="text"

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Comment               note that the key RBS is used for ribosome binding sites

    Feature Key           misc_difference

    Definition            feature sequence is different from that presented
                          in the entry and cannot be described by any other
                          Difference key (conflict, unsure, old_sequence,
                          variation, or modified_base);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /clone="text"
                          /compare=[accession-number.sequence-version]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /phenotype="text"
                          /replace="text"
                          /standard_name="text"

    Comment               the misc_difference feature key should be used to
                          describe variability that arises as a result of
                          genetic manipulation (e.g. site directed mutagenesis);
                          use /replace="" to annotate deletion, e.g.
                          misc_difference 412..433
                                          /replace=""

    Feature Key           misc_feature

    Definition            region of biological interest which cannot be described
                          by any other feature key; a new or rare feature;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /number=unquoted text (single token)
                          /old_locus_tag="text" (single token)
                          /phenotype="text"
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Comment               this key should not be used when the need is merely to
                          mark a region in order to comment on it or to use it in
                          another feature's location

    Feature Key           misc_recomb

    Definition            site of any generalized, site-specific or replicative
                          recombination event where there is a breakage and
                          reunion of duplex DNA that cannot be described by other
                          recombination keys or qualifiers of source key
                          (/proviral);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Molecule scope        DNA

    Feature Key           misc_RNA

    Definition            any transcript or RNA product that cannot be defined by
                          other RNA keys (prim_transcript, precursor_RNA, mRNA,
                          5'UTR, 3'UTR, exon, CDS, sig_peptide, transit_peptide,
                          mat_peptide, intron, polyA_site, ncRNA, rRNA and tRNA);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /product="text"
                          /pseudo
                          /standard_name="text"
                          /trans_splicing

    Feature Key           misc_signal

    Definition            any region containing a signal controlling or altering
                          gene function or expression that cannot be described by
                          other signal keys (promoter, CAAT_signal, TATA_signal,
                          -35_signal, -10_signal, GC_signal, RBS, polyA_signal,
                          enhancer, attenuator, terminator, and rep_origin).

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /phenotype="text"
                          /standard_name="text"

    Feature Key           misc_structure

    Definition            any secondary or tertiary nucleotide structure or
                          conformation that cannot be described by other Structure
                          keys (stem_loop and D-loop);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Feature Key           modified_base

    Definition            the indicated nucleotide is a modified nucleotide and
                          should be substituted for by the indicated molecule
                          (given in the mod_base qualifier value)

    Mandatory qualifiers  /mod_base=<modified_base>

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /frequency="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Comment               value is limited to the restricted vocabulary for
                          modified base abbreviations;

    Feature Key           mRNA

    Definition            messenger RNA; includes 5'untranslated region (5'UTR),
                          coding sequences (CDS, exon) and 3'untranslated region
                          (3'UTR);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /product="text"
                          /pseudo
                          /standard_name="text"
                          /trans_splicing

    Feature Key           ncRNA

    Definition            a non-protein-coding gene, other than ribosomal RNA and
                          transfer RNA, the functional molecule of which is the RNA
                          transcript;

    Mandatory qualifiers  /ncRNA_class="TYPE"

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"
                          /trans_splicing
                          /operon="text"

    Example               /ncRNA_class="miRNA"
                          /ncRNA_class="siRNA"
                          /ncRNA_class="scRNA"

    Comment               the ncRNA feature is not used for ribosomal and transfer
                          RNA annotation, for which the rRNA and tRNA feature keys
                          should be used, respectively;

    Feature Key           N_region

    Definition            extra nucleotides inserted between rearranged
                          immunoglobulin segments.

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref=":"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            CDS

    Organism scope        eukaryotes

    Feature Key           old_sequence

    Definition            the presented sequence revises a previous version of the
                          sequence at this location;

    Mandatory qualifiers  /citation=[number]
                          Or
                          /compare=[accession-number.sequence-version]

    Optional qualifiers   /allele="text"
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /replace="text"

    Comment               /replace="" is used to annotate deletion, e.g.
                          old_sequence 12..15
                          /replace=""
                          NOTE: This feature key is not valid in entries/records
                          created from 15-Oct-2007.

    Feature Key           operon

    Definition            region containing polycistronic transcript
                          containing genes that encode enzymes that are
                          in the same metabolic pathway and regulatory sequences

    Mandatory qualifiers  /operon="text"

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /map="text"
                          /note="text"
                          /phenotype="text"
                          /pseudo
                          /standard_name="text"

    Feature Key           oriT
    Definition            origin of transfer; region of a DNA molecule where transfer is
                          initiated during the process of conjugation or mobilization

    Optional qualifiers   /allele="text"
                          /bound_moiety="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /direction=value
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /rpt_family="text"
                          /rpt_type=<repeat_type>
                          /rpt_unit_range=<base_range>
                          /rpt_unit_seq="text"
                          /standard_name="text"

    Molecule Scope        DNA

    Comment               rep_origin should be used for origins of replication;
                          /direction has legal values RIGHT, LEFT and BOTH, however only
                          RIGHT and LEFT are valid when used in conjunction with the oriT
                          feature;
                          origins of transfer can be present in the chromosome;
                          plasmids can contain multiple origins of transfer

    Feature Key           polyA_signal

    Definition            recognition region necessary for endonuclease cleavage
                          of an RNA transcript that is followed by polyadenylation;
                          consensus=AATAAA [1];

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Organism scope        eukaryotes and eukaryotic viruses

    References            [1] Proudfoot, N. and Brownlee, G.G. Nature 263, 211-214
                          (1976)

    Feature Key           polyA_site

    Definition            site on an RNA transcript to which will be added adenine
                          residues by post-transcriptional polyadenylation;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Organism scope        eukaryotes and eukaryotic viruses

    Feature Key           precursor_RNA

    Definition            any RNA species that is not yet the mature RNA product;
                          may include 5' untranslated region (5'UTR), coding
                          sequences (CDS, exon), intervening sequences (intron)
                          and 3' untranslated region (3'UTR);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /product="text"
                          /standard_name="text"
                          /trans_splicing

    Comment               used for RNA which may be the result of
                          post-transcriptional processing;  if the RNA in question
                          is known not to have been processed, use the
                          prim_transcript key.

    Feature Key           prim_transcript

    Definition            primary (initial, unprocessed) transcript;  includes 5'
                          untranslated region (5'UTR), coding sequences
                          (CDS, exon), intervening sequences (intron) and 3'
                          untranslated region (3'UTR);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /standard_name="text"

    Feature Key           primer_bind

    Definition            non-covalent primer binding site for initiation of
                          replication, transcription, or reverse transcription;
                          includes site(s) for synthetic e.g., PCR primer elements;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /label=feature_label
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"
                          /PCR_conditions="text"

    Comment               used to annotate the site on a given sequence to which a primer
                          molecule binds - not intended to represent the sequence of the
                          primer molecule itself; PCR components and reaction times may
                          be stored under the "/PCR_conditions" qualifier;
                          since PCR reactions most often involve pairs of primers,
                          a single primer_bind key may use the order() operator
                          with two locations, or a pair of primer_bind keys may be
                          used.

    Feature Key           promoter

    Definition            region on a DNA molecule involved in RNA polymerase
                          binding to initiate transcription;

    Optional qualifiers   /allele="text"
                          /bound_moiety="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /phenotype="text"
                          /pseudo
                          /standard_name="text"

    Molecule scope        DNA

    Feature Key           protein_bind

    Definition            non-covalent protein binding site on nucleic acid;

    Mandatory qualifiers  /bound_moiety="text"

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /standard_name="text"

    Comment               note that RBS is used for ribosome binding sites.

    Feature Key           RBS

    Definition            ribosome binding site;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    References            [1] Shine, J. and Dalgarno, L.  Proc Natl Acad Sci USA
                              71, 1342-1346 (1974)
                          [2] Gold, L. et al.  Ann Rev Microb 35, 365-403 (1981)

    Comment               in prokaryotes, known as the Shine-Dalgarno sequence: is
                          located 5 to 9 bases upstream of the initiation codon;
                          consensus GGAGGT [1,2].

    Feature Key           repeat_region

    Definition            region of genome containing repeating units;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /mobile_element=:"<mobile_element_type>
                          [:<mobile_element_name>]"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /rpt_family="text"
                          /rpt_type=<repeat_type>
                          /rpt_unit_range=<base_range>
                          /rpt_unit_seq="text"
                          /satellite="<satellite_type>[:<class>][ <identifier>]"
                          /standard_name="text"

    Comment               mobile_element qualifier replaced /transposon and
                          /insertion_seq qualifiers in December 2006

    Feature Key           rep_origin

    Definition            origin of replication; starting site for duplication of
                          nucleic acid to give two identical copies;

    Optional Qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /direction=value
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /label=feature_label
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Comment               /direction has valid values: RIGHT, LEFT, or BOTH.

    Feature Key           rRNA

    Definition            mature ribosomal RNA; RNA component of the
                          ribonucleoprotein particle (ribosome) which assembles
                          amino acids into proteins.

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Comment               rRNA sizes should be annotated with the /product
                          Qualifier.

    Feature Key           S_region

    Definition            switch region of immunoglobulin heavy chains;
                          involved in the rearrangement of heavy chain DNA leading
                          to the expression of a different immunoglobulin class
                          from the same B-cell;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /gene="text"
                          /gene_synonym="text"
                          /experiment="text"
                          /label=feature_label
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            misc_signal

    Organism scope        eukaryotes

    Feature Key           sig_peptide

    Definition            signal peptide coding sequence; coding sequence for an
                          N-terminal domain of a secreted protein; this domain is
                          involved in attaching nascent polypeptide to the
                          membrane leader sequence;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Feature Key           source

    Definition            identifies the biological source of the specified span of
                          the sequence; this key is mandatory; more than one source
                          key per sequence is allowed; every entry/record will have, as a
                          minimum, either a single source key spanning the entire
                          sequence or multiple source keys, which together, span the
                          entire sequence.

    Mandatory qualifiers  /organism="text"
                          /mol_type="genomic DNA", "genomic RNA", "mRNA", "tRNA",
                                    "rRNA", "other RNA", "other DNA", "transcribed
                                    RNA", "viral cRNA", "unassigned DNA",
                                    "unassigned RNA"

    Optional qualifiers   /bio_material="[<institution-code>:[<collection-code>:]]<material_id>"
                          /cell_line="text"
                          /cell_type="text"
                          /chromosome="text"
                          /citation=[number]
                          /clone="text"
                          /clone_lib="text"
                          /collected_by="text"
                          /collection_date="text"
                          /country="<country_value>[:<region>][, <locality>]"
                          /cultivar="text"
                          /culture_collection="<institution-code>:[<collection-code>:]<culture_id>"
                          /db_xref="<database>:<identifier>"
                          /dev_stage="text"
                          /ecotype="text"
                          /environmental_sample
                          /focus
                          /frequency="text"
                          /germline
                          /haplotype="text"
                          /host="text"
                          /identified_by="text"
                          /isolate="text"
                          /isolation_source="text"
                          /label=feature_label
                          /lab_host="text"
                          /lat_lon="text"
                          /macronuclear
                          /map="text"
                          /mating_type="text"
                          /note="text"
                          /organelle=<organelle_value>
                          /PCR_primers="[fwd_name: XXX, ]fwd_seq: xxxxx,
                          [rev_name: YYY, ]rev_seq: yyyyy"
                          /plasmid="text"
                          /pop_variant="text"
                          /proviral
                          /rearranged
                          /segment="text"
                          /serotype="text"
                          /serovar="text"
                          /sex="text"
                          /specimen_voucher="[<institution-code>:[<collection-code>:]]<specimen_id>"
                          /strain="text"
                          /sub_clone="text"
                          /sub_species="text"
                          /sub_strain="text"
                          /tissue_lib="text"
                          /tissue_type="text"
                          /transgenic
                          /variety="text"

    Molecule scope        any

    Comment               transgenic sequences must have at least two source feature
                          keys; in a transgenic sequence the source feature key
                          describing the organism that is the recipient of the DNA
                          must span the entire sequence;
                          see Appendix IV /organelle for a list of <organelle_value>

    Feature Key           stem_loop

    Definition            hairpin; a double-helical region formed by base-pairing
                          between adjacent (inverted) complementary sequences in a
                          single strand of RNA or DNA.

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /standard_name="text"

    Feature Key           STS

    Definition            sequence tagged site; short, single-copy DNA sequence
                          that characterizes a mapping landmark on the genome and
                          can be detected by PCR; a region of the genome can be
                          mapped by determining the order of a series of STSs;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Molecule scope        DNA

    Parent key            misc_binding

    Comment               STS location to include primer(s) in primer_bind key or
                          primers.

    Feature Key           TATA_signal

    Definition            TATA box; Goldberg-Hogness box; a conserved AT-rich
                          septamer found about 25 bp before the start point of
                          each eukaryotic RNA polymerase II transcript unit which
                          may be involved in positioning the enzyme  for correct
                          initiation; consensus=TATA(A or T)A(A or T) [1,2];

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)

    Organism scope        eukaryotes and eukaryotic viruses

    Molecule scope        DNA

    References            [1] Efstratiadis, A.  et al.  Cell 21, 653-668 (1980)
                          [2] Corden, J., et al.  "Promoter sequences of
                              eukaryotic protein-encoding genes"  Science 209,
                              1406-1414 (1980)

    Feature Key           terminator

    Definition            sequence of DNA located either at the end of the
                          transcript that causes RNA polymerase to terminate
                          transcription;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /operon="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"

    Molecule scope        DNA

    Feature Key           tmRNA

    Definition            transfer messenger RNA; tmRNA acts as a tRNA first,
                          and then as an mRNA that encodes a peptide tag; the
                          ribosome translates this mRNA region of tmRNA and attaches
                          the encoded peptide tag to the C-terminus of the
                          unfinished protein; this attached tag targets the protein for
                          destruction or proteolysis;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"
                          /tag_peptide=<base_range>

    Comment               the tmRNA feature key will become valid on 15-Dec-2007

    Feature Key           transit_peptide

    Definition            transit peptide coding sequence; coding sequence for an
                          N-terminal domain of a nuclear-encoded organellar
                          protein; this domain is involved in post-translational
                          import of the protein into the organelle;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Feature Key           tRNA

    Definition            mature transfer RNA, a small RNA molecule (75-85 bases
                          long) that mediates the translation of a nucleic acid
                          sequence into an amino acid sequence;

    Optional qualifiers   /allele="text"
                          /anticodon=(pos:<base_range>,aa:<amino_acid>)
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"
                          /trans_splicing

    Feature Key           unsure

    Definition            author is unsure of exact sequence in this region;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /compare=[accession-number.sequence-version]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /replace="text"

    Comment               use /replace="" to annotate deletion, e.g.
                          Unsure      11..15
                                      /replace=""

    Feature Key           V_region

    Definition            variable region of immunoglobulin light and heavy
                          chains, and T-cell receptor alpha, beta, and gamma
                          chains;  codes for the variable amino terminal portion;
                          can be composed of V_segments, D_segments, N_regions,
                          and J_segments;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            CDS

    Organism scope        eukaryotes

    Feature Key           V_segment

    Definition            variable segment of immunoglobulin light and heavy
                          chains, and T-cell receptor alpha, beta, and gamma
                          chains; codes for most of the variable region (V_region)
                          and the last few amino acids of the leader peptide;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /product="text"
                          /pseudo
                          /standard_name="text"

    Parent Key            CDS

    Organism scope        eukaryotes

    Feature Key           variation

    Definition            a related strain contains stable mutations from the same
                          gene (e.g., RFLPs, polymorphisms, etc.) which differ
                          from the presented sequence at this location (and
                          possibly others);

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /compare=[accession-number.sequence-version]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /frequency="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /phenotype="text"
                          /product="text"
                          /replace="text"
                          /standard_name="text"

    Comment               used to describe alleles, RFLP's,and other naturally occurring
                          mutations and  polymorphisms; variability arising as a result
                          of genetic manipulation (e.g. site directed mutagenesis) should
                          be described with the misc_difference feature;
                          use /replace="" to annotate deletion, e.g.
                          variation   4..5
                                      /replace=""

    Feature Key           3'UTR

    Definition            region at the 3' end of a mature transcript (following
                          the stop codon) that is not translated into a protein;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"
                          /trans_splicing

    Feature Key           5'UTR

    Definition            region at the 5' end of a mature transcript (preceding
                          the initiation codon) that is not translated into a
                          protein;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /function="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /standard_name="text"
                          /trans_splicing

    Feature Key           -10_signal

    Definition            Pribnow box; a conserved region about 10 bp upstream of
                          the start point of bacterial transcription units which
                          may be involved in binding RNA polymerase;
                          consensus=TAtAaT [1,2,3,4];

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /standard_name="text"

    Organism scope        prokaryotes

    Molecule scope        DNA

    References            [1] Schaller, H., Gray, C., and Hermann, K.  Proc Natl
                              Acad Sci USA 72, 737-741 (1974)
                          [2] Pribnow, D.  Proc Natl Acad Sci USA 72, 784-788 (1974)
                          [3] Hawley, D.K. and McClure, W.R.  "Compilation and
                              analysis of Escherichia coli promoter DNA sequences"
                              Nucl Acid Res 11, 2237-2255 (1983)
                          [4] Rosenberg, M. and Court, D.  "Regulatory sequences
                              involved in the promotion and termination of RNA
                              transcription"  Ann Rev Genet 13, 319-353 (1979)

    Feature Key           -35_signal

    Definition            a conserved hexamer about 35 bp upstream of the start
                          point of bacterial transcription units; consensus=TTGACa
                          or TGTTGACA;

    Optional qualifiers   /allele="text"
                          /citation=[number]
                          /db_xref="<database>:<identifier>"
                          /experiment="text"
                          /gene="text"
                          /gene_synonym="text"
                          /inference="TYPE[ (same species)][:EVIDENCE_BASIS]"
                          /label=feature_label
                          /locus_tag="text" (single token)
                          /map="text"
                          /note="text"
                          /old_locus_tag="text" (single token)
                          /operon="text"
                          /standard_name="text"

    Organism scope        prokaryotes

    Molecule scope        DNA

    References            [1] Takanami, M., et al.  Nature 260, 297-302 (1976)
                          [2] Moran, C.P., Jr., et al.  Molec Gen Genet 186,
                              339-346 (1982)
                          [3] Maniatis, T., et al.  Cell 5, 109-113 (1975)

    7.4 Appendix IV: Summary of qualifiers for feature keys
    7.4.1 Qualifier List

    The following is a list of available qualifiers for feature keys and their usage.
    The information is arranged as follows:

    Qualifier       name of qualifier; qualifier requires a value if followed by an equal
                    sign
    Definition      definition of the qualifier
    Value format    format of value, if required
    Example         example of qualifier with value
    Comment         comments, questions and clarifications

    Qualifier       /allele=
    Definition      name of the allele for the given gene
    Value format    "text"
    Example         /allele="adh1-1"
    Comment         all gene-related features (exon, CDS etc) for a given
                    gene should share the same /allele qualifier value;
                    the /allele qualifier value must, by definition, be
                    different from the /gene qualifier value; when used with
                    the variation feature key, the allele qualifier value
                    should be that of the variant.

    Qualifier       /anticodon=
    Definition      location of the anticodon of tRNA and the amino acid for which
                    it codes
    Value format    (pos:<base_range>,aa:<amino_acid>)  where base_range
                    is the position of the anticodon and amino_acid is the
                    abbreviation for the amino acid encoded
    Example         /anticodon=(pos:34..36,aa:Phe)

    Qualifier       /bio_material=
    Definition      identifier for the biological material from which the nucleic
                    acid sequenced was obtained, with optional institution code and
                    collection code for the place where it is currently stored.
    Value format    "[<institution-code>:[<collection-code>:]]<material_id>"
    Example         /bio_material="CGC:CB3912"      <- Caenorhabditis stock centre
    Comment         the bio_material qualifier should be used to annotate the
                    identifiers of material in biological collections that are not
                    appropriate to annotate as either /specimen_voucher or
                    /culture_collection; these include zoos and aquaria, stock
                    centres, seed banks, germplasm repositories and DNA banks;
                    material_id is mandatory, institution_code and collection_code
                    are optional; institution code is mandatory where collection
                    code is present;
                    the /bio_material qualifier becomes legal on 15-Dec-2007;

    Qualifier       /bound_moiety=
    Definition      name of the molecule/complex that may bind to the
                    given feature
    Value format    "text"
    Example         /bound_moiety="GAL4"
    Comment         Multiple /bound_moiety qualifiers are legal on "promoter"
                    and "enhancer" features. A single /bound_moiety qualifier
                    is legal on the "misc_binding", "oriT" and "protein_bind"
                    features.

    Qualifier       /cell_line=
    Definition      cell line from which the sequence was obtained
    Value format    "text"
    Example         /cell_line="MCF7"

    Qualifier       /cell_type=
    Definition      cell type from which the sequence was obtained
    Value format    "text"
    Example         /cell_type="leukocyte"

    Qualifier       /chromosome=
    Definition      chromosome (e.g. Chromosome number) from which
                    the sequence was obtained
    Value format    "text"
    Example         /chromosome="1"

    Qualifier       /citation=
    Definition      reference to a citation listed in the entry reference field
    Value format    [integer-number] where integer-number is the number of the
                    reference as enumerated in the reference field
    Example         /citation=[3]
    Comment         used to indicate the citation providing the claim of and/or
                    evidence for a feature; brackets are used for conformity.

    Qualifier       /clone=
    Definition      clone from which the sequence was obtained
    Value format    "text"
    Example         /clone="lambda-hIL7.3"
    Comment         not more than one clone should be specified for a given source
                    feature;  to indicate that the sequence was obtained from
                    multiple clones, multiple source features should be given.

    Qualifier       /clone_lib=
    Definition      clone library from which the sequence was obtained
    Value format    "text"
    Example         /clone_lib="lambda-hIL7"

    Qualifier       /codon=
    Definition      specifies a codon which is different from any found in the
                    reference genetic code
    Value format    (seq:"codon-sequence",aa:<amino_acid>) where
                    "codon-sequence" contains the bases of the codon and <amino_acid> is
                    the abbreviation for the translated amino acid, the abbreviation
                    for a modified unusual amino_acids from section 7.5,
                    or the word OTHER
    Example         /codon=(seq:"ttt", aa:Leu)
    Comment         used to specify unusual genetic codes, organellar codes, etc,
                    that are different from the "normal" code for the organism;
                    the codon specified by "seq" codes for the amino acid or stop
                    codon specified by "aa";
                    the codon that is specified is used throughout the CDS;
                    amino acids that are not on the controlled vocabulary list can be
                    annotated by using "aa:OTHER" as the amino acid designation, and
                    by giving the name of the residue in a /note qualifier;
                    only nucleotides a, g, c or t can be used in "codon-sequence";
                    multiple /codon qualifiers should be used to describe ambiguous
                    nucleotides.

    Qualifier       /codon_start=
    Definition      indicates the offset at which the first complete codon of a
                    coding feature can be found, relative to the first base of that
                    feature.
    Value format    1 or 2 or 3
    Example         /codon_start=2

    Qualifier       /collected_by=
    Definition      name of the person who collected the specimen
    Value format    "text"
    Example         /collected_by="Dan Janzen"

    Qualifier       /collection_date=
    Definition      date that the specimen was collected
    Value format    "DD-Mmm-YYYY", "Mmm-YYYY" or "YYYY"
    Example         /collection_date="21-Oct-1952"
                    /collection_date="Oct-1952"
                    /collection_date="1952"
    Comment         full date format DD-Mmm-YYYY is preferred; where day and/or month
                    of collection is not known either "Mmm-YYYY" or "YYYY" can be used;
                    three-letter month abbreviation can be one of the following: Jan,
                    Feb, Mar, Apr, May, Jun, Jul, Aug, Sep, Oct, Nov, Dec.

    Qualifier       /compare=
    Definition      Reference details of an existing public INSD entry
                    to which a comparison is made
    Value format    [accession-number.sequence-version]
    Example         /compare=AJ634337.1
    Comment         This qualifier may be used on the following features:
                    misc_difference, conflict, unsure, old_sequence
                    and variation. The features "old_sequence" and "conflict" must
                    have either a /citation or a /compare qualifier. Multiple /compare
                    qualifiers with different contents are allowed within a
                    single feature.
                    This qualifier is not intended for large-scale annotation
                    of variations, such as SNPs.

    Qualifier       /country=
    Definition      locality of isolation of the sequenced organism indicated in
                    terms of political names for nations, oceans or seas, followed
                    by regions and localities
    Value format    "<country_value>[:<region>][, <locality>]" where
                    country_value is any value from the controlled vocabulary at
                    http://www.insdc.org/page.php?page=country
    Example         /country="Canada:Vancouver"
                    /country="France:Cote d'Azur, Antibes"
                    /country="Atlantic Ocean:Charlie Gibbs Fracture Zone"
    Comment         Intended to provide a reference to the site where the source
                    organism was isolated or sampled. Regions and localities should
                    be indicated where possible. Note that the physical geography of
                    the isolation or sampling site should be represented in
                    /isolation_source.

    Qualifier       /cultivar=
    Definition      cultivar (cultivated variety) of plant from which sequence was
                    obtained.
    Value format    "text"
    Example         /cultivar="Nipponbare"
                    /cultivar="Tenuifolius"
                    /cultivar="Candy Cane"
                    /cultivar="IR36"
    Comment         'cultivar' is applied solely to products of artificial
                    selection;  use the variety qualifier for natural, named
                    plant and fungal varieties;

    Qualifier       /culture_collection=
    Definition      institution code and identifier for the culture from which the
                    nucleic acid sequenced was obtained, with optional collection
                    code.
    Value format    "<institution-code>:[<collection-code>:]<culture_id>"
    Example         /culture_collection="ATCC:26370"
    Comment         the /culture_collection qualifier should be used to annotate
                    live microbial and viral cultures, and cell lines that have been
                    deposited in curated culture collections; microbial cultures in
                    personal or laboratory collections should be annotated in strain
                    qualifiers;
                    annotation with a culture_collection qualifier implies that the
                    sequence was obtained from a sample retrieved (by the submitter
                    or a collaborator) from the indicated culture collection, or
                    that the sequence was obtained from a sample that was deposited
                    (by the submitter or a collaborator) in the indicated culture
                    collection; annotation with more than one culture_collection
                    qualifier indicates that the sequence was obtained from a sample
                    that was deposited (by the submitter or a collaborator) in more
                    than one culture collection.
                    culture_id and institution_code are mandatory, collection_code
                    is optional;
                    the /culture_collection qualifier becomes legal on 15-Dec-2007;

    Qualifier       /db_xref=
    Definition      database cross-reference: pointer to related information in
                    another database.
    Value format    "<database:identifier>" where database is
                    the name of the database containing related information, and
                    identifier is the internal identifier of the related information
                    according to the naming conventions of the cross-referenced
                    database.
    Example         /db_xref="UniProtKB/Swiss-Prot:P28763"
    Comment         the complete list of allowed database types is kept at
                    http://www.insdc.org/page.php?page=db_xref

    Qualifier       /dev_stage=
    Definition      if the sequence was obtained from an organism in a specific
                    developmental stage, it is specified with this qualifier
    Value format    "text"
    Example         /dev_stage="fourth instar larva"

    Qualifier       /direction=
    Definition      direction of DNA replication
    Value format    left, right, or both where left indicates toward the 5' end of
                    the entry sequence (as presented) and right indicates toward
                    the 3' end
    Example         /direction=LEFT

    Qualifier       /EC_number=
    Definition      Enzyme Commission number for enzyme product of sequence
    Value format    "text"
    Example         /EC_number="1.1.2.4"
                    /EC_number="1.1.2.-"
                    /EC_number="1.1.2.n"
    Comment         valid values for EC numbers are defined in the list prepared by the
                    Nomenclature Committee of the International Union of Biochemistry and
                    Molecular Biology (NC-IUBMB) (published in Enzyme Nomenclature 1992,
                    Academic Press, San Diego, or a more recent revision thereof).
                    The format represents a string of four numbers separated by full
                    stops; up to three numbers starting from the end of the string can
                    be replaced by dash "." to indicate uncertain assignment.
                    Symbol "n" can be used in the last position instead of a number
                    where the EC number is awaiting assignment. Please note that such
                    incomplete EC numbers are not approved by NC-IUBMB.

    Qualifier       /ecotype=
    Definition      a population within a given species displaying genetically
                    based, phenotypic traits that reflect adaptation to a local habitat.
    Value Format    "text"
    Example         /ecotype="Columbia"
    Comment         an example of such a population is one that has adapted hairier
                    than normal leaves as a response to an especially sunny habitat.
                    'Ecotype' is often applied to standard genetic stocks of
                    Arabidopsis thaliana, but it can be applied to any sessile
                    organism.

    Qualifier       /environmental_sample
    Definition      identifies sequences derived by direct molecular
                    isolation from a bulk environmental DNA sample
                    (by PCR with or without subsequent cloning of the
                    product, DGGE, or other anonymous methods) with no
                    reliable identification of the source organism.
                    Environmental samples include clinical samples,
                    gut contents, and other sequences from anonymous
                    organisms that may be associated with a particular
                    host. They do not include endosymbionts that can be
                    reliably recovered from a particular host, organisms
                    from a readily identifiable but uncultured field sample
                    (e.g., many cyanobacteria), or phytoplasmas that can be
                    reliably recovered from diseased plants (even though
                    these cannot be grown in axenic culture).
    Value format    none
    Example         /environmental_sample
    Comment         used only with the source feature key; source feature
                    keys containing the /environmental_sample qualifier
                    should also contain the /isolation_source qualifier.
                    entries including /environmental_sample must not include
                    the /strain qualifier

    Qualifier       /estimated_length=
    Definition      estimated length of the gap in the sequence
    Value format    unknown or <integer>
    Example         /estimated_length=unknown
                    /estimated_length=342

    Qualifier       /exception=
    Definition      indicates that the coding region cannot be translated using
                    standard biological rules
    Value format    "RNA editing", "reasons given in citation",
                    "rearrangement required for product"
    Example         /exception="RNA editing"
                    /exception="reasons given in citation"
                    /exception="rearrangement required for product"
    Comment         only to be used to describe biological mechanisms such
                    as RNA editing;  where the exception cannot easily be described
                    a published citation must be referred to; protein translation of
                    /exception CDS will be different from the according conceptual
                    translation;
                    - must not be used where transl_except would be adequate,
                      e.g. in case of stop codon completion use:
                    /transl_except=(pos:6883,aa:TERM)
                    /note="TAA stop codon is completed by addition of 3' A residues to
                    mRNA".
                    - must not be used for ribosomal slippage, instead use join operator,
                      e.g.: CDS   join(486..1784,1787..4810)
                                  /note="ribosomal slip on tttt sequence at 1784..1787"

    Qualifier       /experiment=
    Definition      a brief description of the nature of the experimental
                    evidence that supports the feature identification or assignment.
    Value format    "text"
    Example         /experiment="Northern blot"
                    /experiment="heterologous expression system of Xenopus laevis
                    oocytes"
    Comment         detailed experimental details should not be included, and would
                    normally be found in the cited publications; value
                    "experimental evidence, no additional details recorded" was used to
                    replace instances of /evidence=EXPERIMENTAL in December 2005

    Qualifier       /focus
    Definition      identifies the source feature of primary biological
                    interest for records that have multiple source features
                    originating from different organisms and that are not
                    transgenic.
    Value format    none
    Example         /focus
    Comment         the source feature carrying the /focus qualifier
                    identifies the main organism of the entry, this
                    determines: a) the name displayed in the organism
                    lines, b) if no translation table is specified, the
                    translation table, c) the DDBJ/EMBL/GenBank taxonomic
                    division in which the entry will appear; only one
                    source feature with /focus is allowed in an entry; the
                    /focus and /transgenic qualifiers are mutually exclusive
                    in an entry.

    Qualifier       /frequency=
    Definition      frequency of the occurrence of a feature
    Value format    text representing the proportion of a population carrying the
                    feature expressed as a fraction
    Example         /frequency="23/108"
                    /frequency="1 in 12"
                    /frequency=".85"

    Qualifier       /function=
    Definition      function attributed to a sequence
    Value format    "text"
    Example         function="essential for recognition of cofactor"
    Comment         /function is used when the gene name and/or product name do not
                    convey the function attributable to a sequence.

    Qualifier       /gene=
    Definition      symbol of the gene corresponding to a sequence region
    Value format    "text"
    Example         /gene="ilvE"

    Qualifier       /gene_synonym=
    Definition      synonymous, replaced, obsolete or former gene symbol
    Value format    "text"
    Example         /gene_synonym="Hox-3.3"
                    in a feature where /gene="Hoxc6"
    Comment         used where it is helpful to indicate a gene symbol
                    synonym; when used, a primary gene symbol must always be
                    indicated in /gene

    Qualifier       /germline
    Definition      the sequence presented in the entry has not undergone somatic
                    rearrangement as part of an adaptive immune response; it is the
                    unrearranged sequence that was inherited from the parental
                    germline
    Value format    none
    Example         /germline
    Comment         /germline should not be used to indicate that the source of
                    the sequence is a gamete or germ cell;
                    /germline and /rearranged cannot be used in the same source
                    feature;
                    /germline and /rearranged should only be used for molecules that
                    can undergo somatic rearrangements as part of an adaptive immune
                    response; these are the T-cell receptor (TCR) and immunoglobulin
                    loci in the jawed vertebrates, and the unrelated variable
                    lymphocyte receptor (VLR) locus in the jawless fish (lampreys
                    and hagfish);
                    /germline and /rearranged should not be used outside of the
                    Craniata (taxid=89593)

    Qualifier       /haplotype=
    Definition      name for a specific set of alleles that are linked together
                    on the same physical chromosome. In the absence of
                    recombination,each haplotype is inherited as a unit, and may
                    be used to track gene flow in populations.
    Value format    "text"
    Example         /haplotype="Dw3 B5 Cw1 A1"

    Qualifier       /host=
    Definition      natural (as opposed to laboratory) host to the organism from
                    which sequenced molecule was obtained
    Value format    "text"
    Example         /host="Homo sapiens"
                    /host="Homo sapiens 12 year old girl"
                    /host="Rhizobium NGR234"

    Qualifier       /identified_by=
    Definition      name of the taxonomist who identified the specimen
    Value format    "text"
    Example         /identified_by="John Burns"

    Qualifier       /inference=
    Definition      a structured description of non-experimental evidence that supports
                    the feature identification or assignment.

    Value format   "TYPE[ (same species)][:EVIDENCE_BASIS]"
    where TYPE is one of the following:
    "non-experimental evidence, no additional details recorded"
         "similar to sequence"
              "similar to AA sequence"
              "similar to DNA sequence"
              "similar to RNA sequence"
                  "similar to RNA sequence, mRNA"
                  "similar to RNA sequence, EST"
                  "similar to RNA sequence, other RNA"
         "profile"
              "nucleotide motif"
              "protein motif"
              "ab initio prediction"
         "alignment"
    where the optional text "(same species)" is included when the inference comes
    from the same species as the entry.
    where the optional "EVIDENCE_BASIS" is either a reference to a database entry
    (including accession and version) or an algorithm (including version) , eg
    'INSD:AACN010222672.1', 'InterPro:IPR001900', 'ProDom:PD000600',
    'Genscan:2.0', etc.

    Example         /inference="similar to DNA sequence:INSD:AY411252.1"
                    /inference="similar to RNA sequence, mRNA:RefSeq:NM_000041.2"
                    /inference="similar to DNA sequence (same
                    species):INSD:AACN010222672.1"
                    /inference="profile:tRNAscan:2.1"
                    /inference="protein motif:InterPro:IPR001900"
                    /inference="ab initio prediction:Genscan:2.0"
                    /inference="alignment:Splign:1.0"

    Comment         /inference="non-experimental evidence, no additional details
                    recorded" was used to replace instances of
                    /evidence=NOT_EXPERIMENTAL in December 2005;
                    recommentations for choice of resource acronym for
                    [EVIDENCE_BASIS] are provided in the /inference qualifier
                    vocabulary recommendation document
                    (http://www.insdc.org/page.php?page=inference);

    Qualifier       /isolate=
    Definition      individual isolate from which the sequence was obtained
    Value format    "text"
    Example         /isolate="Patient #152"
                    /isolate="DGGE band PSBAC-13"

    Qualifier       /isolation_source=
    Definition      describes the physical, environmental and/or local
                    geographical source of the biological sample from which
                    the sequence was derived
    Value format    "text"
    Examples        /isolation_source="rumen isolates from standard
                    Pelleted ration-fed steer #67"
                    /isolation_source="permanent Antarctic sea ice"
                    /isolation_source="denitrifying activated sludge from
                    carbon_limited continuous reactor"
    Comment         used only with the source feature key;
                    source feature keys containing an /environmental_sample
                    qualifier should also contain an /isolation_source
                    qualifier; the /country qualifier should be used to
                    describe the country and major geographical sub-region.

    Qualifier       /label=
    Definition      a label used to permanently tag a feature
    Value format    feature_label
    Example         /label=Alb1_exon1
    Comment         feature labels follow the naming conventions
                    for all feature table objects
                    (see Sections 3.1 and 3.4)

    Qualifier       /lab_host=
    Definition      scientific name of the laboratory host used to propagate the
                    source organism from which the sequenced molecule was obtained
    Value format    "text"
    Example         /lab_host="Gallus gallus"
                    /lab_host="Gallus gallus embryo"
                    /lab_host="Escherichia coli strain DH5 alpha"
                    /lab_host="Homo sapiens HeLa cells"
    Comment         the full binomial scientific name of the host organism should
                    be used when known; extra conditional information relating to
                    the host may also be included

    Qualifier       /lat_lon=
    Definition      geographical coordinates of the location where the specimen was
                    collected
    Value format    "text"
    Example         /lat_lon="47.94 N 28.12 W"
                    /lat_lon="45.01 S 4.12 E"
    Comment         degrees latitude and longitude in format "d[d.dd] N|S d[dd.dd] W|E"
                    (see the examples)

    Qualifier       /locus_tag=
    Definition      a submitter-supplied, systematic, stable identifier for a gene
                    and its associated features, used for tracking purposes
    Value Format    "text"(single token)
                    but not "<1-5 letters><5-9 digit integer>[.<integer>]"
    Example         /locus_tag="ABC_0022"
                    /locus_tag="A1C_00001"
    Comment         /locus_tag can be used with any feature that /gene
                    can be used with;
                    identical /locus_tag values may be used within an entry/record,
                    but only if the identical /locus_tag values are associated
                    with the same gene; in all other circumstances the /locus_tag
                    value must be unique within that entry/record. Multiple /locus_tag
                    values are not allowed within one feature for entries created
                    after 15-OCT-2004.
                    If a /locus_tag needs to be re-assigned the /old_locus_tag qualifier
                    should be used to store the old value. The /locus_tag value should
                    not be in a format which resembles INSD accession numbers,
                    accession.version, or /proteid_id identifiers.

    Qualifier       /map=
    Definition      genomic map position of feature
    Value format    "text"
    Example         /map="8q12-13"

    Qualifier       /macronuclear
    Definition      if the sequence shown is DNA and from an organism which
                    undergoes chromosomal differentiation between macronuclear and
                    micronuclear stages, this qualifier is used to denote that the
                    sequence is from macronuclear DNA.
    Value format    none
    Example         /macronuclear

    Qualifier       /mating_type=
    Definition      mating type of the organism from which the sequence was
                    obtained; mating type is used for prokaryotes, and for
                    eukaryotes that undergo meiosis without sexually dimorphic
                    gametes
    Value format    "text"
    Examples        /mating_type="MAT-1"
                    /mating_type="plus"
                    /mating_type="-"
                    /mating_type="odd"
                    /mating_type="even"
    Comment         /mating_type="male" and /mating_type="female" are
                    valid in the prokaryotes, but not in the eukaryotes;
                    for more information, see the entry for /sex.

    Qualifier       /mobile_element=
    Definition      type and name or identifier of the mobile element which is
                    described by the parent feature
    Value format    "<mobile_element_type>[:<mobile_element_name>]" where
                    mobile_element_type is one of the following:
                    "transposon", "retrotransposon", "integron",
                    "insertion sequence", "non-LTR retrotransposon",
                    "SINE", "MITE", "LINE", "other".
    Example         /mobile_element="transposon:Tnp9"
    Comment         /mobile_element is legal on repeat_region feature key only.
                    Mobile element should be used to represent both elements which
                    are currently mobile, and those which were mobile in the past.
                    Value "other" requires a mobile_element_name.
                    /mobile_element qualifier replaced /transposon and /insertion_seq
                    qualifiers in December 2006

    Qualifier       /mod_base=
    Definition      abbreviation for a modified nucleotide base
    Value format    modified_base
    Example         /mod_base=m5c
    Comment         modified nucleotides not found in the restricted vocabulary
                    list can be annotated by entering '/mod_base=OTHER' with
                    '/note="name of modified base"'

    Qualifier       /mol_type=
    Definition      in vivo molecule type of sequence
    Value format    "genomic DNA", "genomic RNA", "mRNA", "tRNA", "rRNA", "other
                    RNA", "other DNA", "transcribed RNA", "viral cRNA", "unassigned
                    DNA", "unassigned RNA"
    Example         /mol_type="genomic DNA"
    Comment         all values refer to the in vivo or synthetic molecule for
                    primary entries and the hypothetical molecule in Third Party
                    Annotation entries; the value "genomic DNA" does not imply that
                    the molecule is nuclear (e.g. organelle and plasmid DNA should
                    be described using "genomic DNA"); ribosomal RNA genes should be
                    described using "genomic DNA"; "rRNA" should only be used if the
                    ribosomal RNA molecule itself has been sequenced; /mol_type is
                    mandatory on every source feature key; all /mol_type values
                    within one entry/record must be the same; values "other RNA" and
                    "other DNA" should be applied to synthetic molecules, values
                    "unassigned DNA", "unassigned RNA" should be applied where in
                    vivo molecule is unknown

    Qualifier       /ncRNA_class=
    Definition      a structured description of the classification of the
                    non-coding RNA described by the ncRNA parent key
    Value format   "TYPE"
    Example         /ncRNA_class="miRNA"
                    /ncRNA_class="siRNA"
                    /ncRNA_class="scRNA"
    Comment         TYPE is a term taken from the INSDC controlled vocabulary for ncRNA
                    classes (http://www.insdc.org/page.php?page=rna_vocab); on
                    15-Oct-2008, the following terms were valid:

                          "antisense_RNA"
                          "autocatalytically_spliced_intron"
                          "ribozyme"
                          "hammerhead_ribozyme"
                          "RNase_P_RNA"
                          "RNase_MRP_RNA"
                          "telomerase_RNA"
                          "guide_RNA"
                          "rasiRNA"
                          "scRNA"
                          "siRNA"
                          "miRNA"
                          "piRNA"
                          "snoRNA"
                          "snRNA"
                          "SRP_RNA"
                          "vault_RNA"
                          "Y_RNA"
                          "other"

                    ncRNA classes not yet in the INSDC /ncRNA_class controlled
                    vocabulary can be annotated by entering
                    '/ncRNA_class="other"' with '/note="[brief explanation of
                    novel ncRNA_class]"';

    Qualifier       /note=
    Definition      any comment or additional information
    Value format    "text"
    Example         /note="This qualifier is equivalent to a comment."

    Qualifier       /number=
    Definition      a number to indicate the order of genetic elements (e.g.,
                    exons or introns) in the 5' to 3' direction
    Value format    unquoted text (single token)
    Example         /number=4
                    /number=6B
    Comment         text limited to integers, letters or combination of integers and/or
                    letters represented as an unquoted single token (e.g. 5a, XIIb);
                    any additional terms should be included in /standard_name.
                    Example:  /number=2A
                              /standard_name="long"

    Qualifier       /old_locus_tag=
    Definition      feature tag assigned for tracking purposes
    Value Format    "text" (single token)
    Example         /old_locus_tag="RSc0382"
                    /locus_tag="YPO0002"
    Comment         /old_locus_tag can be used with any feature where /gene is valid and
                    where a /locus_tag qualifier is present.
                    Identical /old_locus_tag values may be used within an entry/record,
                    but only if the identical /old_locus_tag values are associated
                    with the same gene; in all other circumstances the /old_locus_tag
                    value must be unique within that entry/record.
                    Multiple/old_locus_tag qualifiers with distinct values are
                    allowed within a single feature; /old_locus_tag and /locus_tag
                    values must not be identical within a single feature.

    Qualifier       /operon=
    Definition      name of the group of contiguous genes transcribed into a
                    single transcript to which that feature belongs.
    Value format    "text"
    Example         /operon="lac"
    Comment         currently valid only on Prokaryota-specific features

    Qualifier       /organelle=
    Definition      type of membrane-bound intracellular structure from which the
                    sequence was obtained
    Value format    mitochondrion, nucleomorph, plastid, mitochondrion:kinetoplast,
                    plastid:chloroplast, plastid:apicoplast, plastid:chromoplast,
                    plastid:cyanelle, plastid:leucoplast, plastid:proplastid,
    Examples        /organelle="chromatophore"
                    /organelle="hydrogenosome"
                    /organelle="mitochondrion"
                    /organelle="nucleomorph"
                    /organelle="plastid"
                    /organelle="mitochondrion:kinetoplast"
                    /organelle="plastid:chloroplast"
                    /organelle="plastid:apicoplast"
                    /organelle="plastid:chromoplast"
                    /organelle="plastid:cyanelle"
                    /organelle="plastid:leucoplast"
                    /organelle="plastid:proplastid"
    Comments        modifier text limited to values from controlled list

    Qualifier       /organism=
    Definition      scientific name of the organism that provided the
                    sequenced genetic material.
    Value format    "text"
    Example         /organism="Homo sapiens"
    Comment         the organism name which appears on the OS or ORGANISM line
                    will match the value of the /organism qualifier of the
                    source key in the simplest case of a one-source sequence.

    Qualifier       /partial
    Definition      differentiates between complete regions and partial ones
    Value format    none
    Example         /partial
    Comment         not to be used for new entries from 15-DEC-2001;
                    use '<' and '>' signs in the location descriptors to
                    indicate that the sequence is partial.

    Qualifier       /PCR_conditions=
    Definition      description of reaction conditions and components for PCR
    Value format    "text"
    Example         /PCR_conditions="Initial denaturation:94degC,1.5min"
    Comment         used with primer_bind key

    Qualifier       /PCR_primers=
    Definition      PCR primers that were used to amplify the sequence.
                    A single /PCR_primers qualifier should contain all the primers used
                    for a single PCR reaction. If multiple forward or reverse primers are
                    present in a  single PCR reaction, multiple sets of fwd_name/fwd_seq
                    or rev_name/rev_seq values will be  present.
    Value format    /PCR_primers="[fwd_name: XXX1, ]fwd_seq: xxxxx1,[fwd_name: XXX2,]
                    fwd_seq: xxxxx2, [rev_name: YYY1, ]rev_seq: yyyyy1,
                    [rev_name: YYY2, ]rev_seq: yyyyy2"

    Example         /PCR_primers="fwd_name: CO1P1, fwd_seq: ttgattttttggtcayccwgaagt,
                    rev_name: CO1R4, rev_seq: ccwvytardcctarraartgttg"
                    /PCR_primers=" fwd_name: hoge1, fwd_seq: cgkgtgtatcttact,
                    rev_name: hoge2, rev_seq: cg<i>gtgtatcttact"
                    /PCR_primers="fwd_name: CO1P1, fwd_seq: ttgattttttggtcayccwgaagt,
                    fwd_name: CO1P2, fwd_seq: gatacacaggtcayccwgaagt, rev_name: CO1R4,
                    rev_seq: ccwvytardcctarraartgttg"

    Comment         fwd_seq and rev_seq are both mandatory; fwd_name and rev_name are
                    both optional. Both sequences should be presented in 5'>3' order.
                    The sequences should be given in the IUPAC degenerate-base alphabet,
                    except for the modified bases; those must be enclosed within angle
                    brackets <>

    Qualifier       /phenotype=
    Definition      phenotype conferred by the feature, where phenotype is defined as a
                    physical, biochemical or behavioural characteristic or set of
                    characteristics
    Value format    "text"
    Example         /phenotype="erythromycin resistance"

    Qualifier       /pop_variant=
    Definition      name of a variation that characterizes a particular
                    sub-population within a given species. The variation could be
                    in the genotype or the phenotype.
    Value format    "text"
    Example         /pop_variant="pop1"
                    /pop_variant="Bear Paw"

    Qualifier       /plasmid=
    Definition      name of naturally occurring plasmid from which the sequence was
                    obtained, where plasmid is defined as an independently replicating
                    genetic unit that cannot be described by /chromosome or /segment
    Value format    "text"
    Example         /plasmid="C-589"

    Qualifier       /product=
    Definition      name of the product associated with the feature, e.g. the mRNA of an
                    mRNA feature, the polypeptide of a CDS, the mature peptide of a
                    mat_peptide, etc.
    Value format    "text"
    Example         /product="trypsinogen" (when qualifier appears in CDS feature)
                    /product="trypsin" (when qualifier appears in mat_peptide feature)
                    /product="XYZ neural-specific transcript" (when qualifier appears in
                    mRNA feature)

    Qualifier       /protein_id=
    Definition      protein identifier, issued by International collaborators.
                    this qualifier consists of a stable ID portion (3+5 format
                    with 3 position letters and 5 numbers) plus a version number
                    after the decimal point.
    Value format    <identifier>
    Example         /protein_id="AAA12345.1"
    Comment         when the protein sequence encoded by the CDS changes, only
                    the version number of the /protein_id value is incremented;
                    the stable part of the /protein_id remains unchanged and as a
                    result will permanently be associated with a given protein;
                    this qualifier is valid only on CDS features which translate
                    into a valid protein.

    Qualifier       /proviral
    Definition      this qualifier is used to flag sequence obtained from a virus or
                    phage that is integrated into the genome of another organism
    Value format    none
    Example         /proviral

    Qualifier       /pseudo
    Definition      indicates that this feature is a non-functional version of the
                    element named by the feature key
    Value format    none
    Example         /pseudo

    Qualifier       /rearranged
    Definition      the sequence presented in the entry has undergone somatic
                    rearrangement as part of an adaptive immune response; it is not
                    the unrearranged sequence that was inherited from the parental
                    germline
    Value format    none
    Example         /rearranged
    Comment         /rearranged should not be used to annotate chromosome
                    rearrangements that are not involved in an adaptive immune
                    response;
                    /germline and /rearranged cannot be used in the same source
                    feature;
                    /germline and /rearranged should only be used for molecules that
                    can undergo somatic rearrangements as part of an adaptive immune
                    response; these are the T-cell receptor (TCR) and immunoglobulin
                    loci in the jawed vertebrates, and the unrelated variable
                    lymphocyte receptor (VLR) locus in the jawless fish (lampreys
                    and hagfish);
                    /germline and /rearranged should not be used outside of the
                    Craniata (taxid=89593)

    Qualifier       /replace=
    Definition      indicates that the sequence identified a feature's intervals is
                    replaced by the sequence shown in "text"; if no sequence is
                    contained within the qualifier, this indicates a deletion.
    Value format    "text"
    Example         /replace="a"
                    /replace=""

    Qualifier       /ribosomal_slippage
    Definition      during protein translation, certain sequences can program
                    ribosomes to change to an alternative reading frame by a
                    mechanism known as ribosomal slippage
    Value format    none
    Example         /ribosomal_slippage
    Comment         a join operator,e.g.: [join(486..1784,1787..4810)] should be used
                    in the CDS spans to indicate the location of ribosomal_slippage

    Qualifier       /rpt_family=
    Definition      type of repeated sequence; "Alu" or "Kpn", for example
    Value format    "text"
    Example         /rpt_family="Alu"

    Qualifier       /rpt_type=
    Definition      organization of repeated sequence
    Value format    tandem, inverted, flanking, terminal, direct, dispersed, and other
    Example         /rpt_type=INVERTED
    Comment         the values are case-insensitive, i.e. both "INVERTED" and "inverted"
                    are valid;
                    Definitions of the values:
                    tandem, a repeat that exists adjacent to another in the same
                    orientation;
                    inverted, a repeat which occurs as part of as set (normally a part)
                    organized in the reverse orientation;
                    flanking, a repeat lying outside the sequence for which it has
                    functional significance (eg. transposon insertion target sites);
                    terminal, a repeat at the ends of and within the sequence for which
                    it has functional significance (eg. transposon LTRs);
                    direct, a repeat that exists not always adjacent but is in the same
                    orientation;
                    dispersed, a repeat that is found dispersed throughout the genome;
                    other, a repeat exhibiting important attributes that cannot be
                    described by other values.

    Qualifier       /rpt_unit_range=
    Definition      identity of a repeat range
    Value format    <base_range>
    Example         /rpt_unit_range=202..245
    Comment         used to indicate the base range of the sequence that constitutes
                    a repeated sequence specified by the feature keys oriT and
                    repeat_region; qualifiers /rpt_unit_range and /rpt_unit_seq
                    replaced qualifier /rpt_unit in December 2005

    Qualifier       /rpt_unit_seq=
    Definition      identity of a repeat sequence
    Value format    "text"
    Example         /rpt_unit_seq="aagggc"
                    /rpt_unit_seq="ag(5)tg(8)"
                    /rpt_unit_seq="(AAAGA)6(AAAA)1(AAAGA)12"
    Comment         used to indicate the literal sequence that constitutes a
                    repeated sequence specified by the feature keys oriT and
                    repeat_region; qualifiers /rpt_unit_range and /rpt_unit_seq
                    replaced qualifier /rpt_unit in December 2005

    Qualifier       /satellite=
    Definition      identifier for a satellite DNA marker, compose of many tandem
                    repeats (identical or related) of a short basic repeated unit;
    Value format    "<satellite_type>[:<class>][ <identifier>]"
                    where satellite_type is one of the following
                        "satellite", "microsatellite", "minisatellite"
    Example         /satellite="satellite: S1a"
                    /satellite="satellite: alpha"
                    /satellite="satellite: gamma III"
                    /satellite="microsatellite: DC130"
    Comment         many satellites have base composition or other properties
                    that differ from those of the rest of the genome that allows
                    them to be identified.

    Qualifier       /segment=
    Definition      name of viral or phage segment sequenced
    Value format    "text"
    Example         /segment="6"

    Qualifier       /serotype=
    Definition      serological variety of a species characterized by its
                    antigenic properties
    Value format    "text"
    Example         /serotype="B1"
    Comment         used only with the source feature key;
                    the Bacteriological Code recommends the use of the
                    term 'serovar' instead of 'serotype' for the
                    prokaryotes; see the International Code of Nomenclature
                    of Bacteria (1990 Revision) Appendix 10.B "Infraspecific
                    Terms".

    Qualifier       /serovar=
    Definition      serological variety of a species (usually a prokaryote)
                    characterized by its antigenic properties
    Value format    "text"
    Example         /serovar="O157:H7"
    Comment         used only with the source feature key;
                    the Bacteriological Code recommends the use of the
                    term 'serovar' instead of 'serotype' for prokaryotes;
                    see the International Code of Nomenclature of Bacteria
                    (1990 Revision) Appendix 10.B "Infraspecific Terms".

    Qualifier       /sex=
    Definition      sex of the organism from which the sequence was obtained;
                    sex is used for eukaryotic organisms that undergo meiosis
                    and have sexually dimorphic gametes
    Value format    "text"
    Examples        /sex="female"
                    /sex="male"
                    /sex="hermaphrodite"
                    /sex="unisexual"
                    /sex="bisexual"
                    /sex="asexual"
                    /sex="monoecious" [or monecious]
                    /sex="dioecious" [or diecious]
    Comment         /sex should be used (instead of /mating_type)
                    in the Metazoa, Embryophyta, Rhodophyta & Phaeophyceae;
                    /mating_type should be used (instead of /sex)
                    in the Bacteria, Archaea & Fungi;
                    neither /sex nor /mating_type should be used
                    in the viruses;
                    outside of the taxa listed above, /mating_type
                    should be used unless the value of the qualifier
                    is taken from the vocabulary given in the examples
                    above

    Qualifier       /specimen_voucher=
    Definition      identifier for the specimen from which the nucleic acid
                    sequenced was obtained
    Value format    /specimen_voucher="[<institution-code>:[<collection-code>:]]<specimen_id>"
    Example         /specimen_voucher="UAM:Mamm:52179"
                    /specimen_voucher="AMCC:101706"
                    /specimen_voucher="USNM:field series 8798"
                    /specimen_voucher="personal collection:Dan Janzen:99-SRNP-2003"
                    /specimen_voucher="99-SRNP-2003"
    Comment         the /specimen_voucher qualifier is intended to annotate a
                    reference to the physical specimen that remains after the
                    sequence has been obtained;
                    if the specimen was destroyed in the process of sequencing,
                    electronic images (e-vouchers) are an adequate substitute for a
                    physical voucher specimen; ideally the specimens will be
                    deposited in a curated museum, herbarium, or frozen tissue
                    collection, but often they will remain in a personal or
                    laboratory collection for some time before they are deposited in
                    a curated collection;
                    there are three forms of specimen_voucher qualifiers; if the
                    text of the qualifier includes one or more colons it is a
                    'structured voucher'; structured vouchers include
                    institution-codes (and optional collection-codes) taken from a
                    controlled vocabulary that denotes the museum or herbarium
                    collection where the specimen resides;

    Qualifier       /standard_name=
    Definition      accepted standard name for this feature
    Value format    "text"
    Example         /standard_name="dotted"
    Comment         use /standard_name to give full gene name, but use /gene to
                    give gene symbol (in the above example /gene="Dt").

    Qualifier       /strain=
    Definition      strain from which sequence was obtained
    Value format    "text"
    Example         /strain="BALB/c"
    Comment         entries including /strain must not include
                    the /environmental_sample qualifier

    Qualifier       /sub_clone=
    Definition      sub-clone from which sequence was obtained
    Value format    "text"
    Example         /sub_clone="lambda-hIL7.20g"
    Comment         the comments on /clone apply to /sub_clone

    Qualifier       /sub_species=
    Definition      name of sub-species of organism from which sequence was
                    obtained
    Value format    "text"
    Example         /sub_species="lactis"

    Qualifier       /sub_strain=
    Definition      name or identifier of a genetically or otherwise modified
                    strain from which sequence was obtained, derived from a
                    parental strain (which should be annotated in the /strain
                    qualifier).sub_strain from which sequence was obtained
    Value format    "text"
    Example         /sub_strain="abis"
    Comment         If the parental strain is not given, this should
                    be annotated in the strain qualifier instead of sub_strain.
                    Either:
                    /strain="K-12"
                    /sub_strain="MG1655"
                    or:
                    /strain="MG1655"

    Qualifier       /tag_peptide=
    Definition      base location encoding the polypeptide for proteolysis tag of
                    tmRNA and its termination codon;
    Value format    <base_range>
    Example         /tag_peptide=90..122
    Comment         it is recommended that the amino acid sequence corresponding
                    to the /tag_peptide be annotated by describing a 5' partial
                    CDS feature; e.g. CDS    <90..122;
                    the /tag_peptide qualifier (and tmRNA feature) will become
                    valid on 15-Dec-2007

    Qualifier       /tissue_lib=
    Definition      tissue library from which sequence was obtained
    Value format    "text"
    Example         /tissue_lib="tissue library 772"

    Qualifier       /tissue_type=
    Definition      tissue type from which the sequence was obtained
    Value format    "text"
    Example         /tissue_type="liver"

    Qualifier       /transgenic
    Definition      identifies the source feature of the organism which was
                    the recipient of transgenic DNA.
    Value format    none
    Example         /transgenic
    Comment         transgenic sequences must have at least two source feature keys;
                    the source feature key having the /transgenic qualifier must
                    span the whole sequence; the source feature carrying the
                    /transgenic qualifier identifies the main organism of the entry,
                    this determines: a) the name displayed in the organism lines,
                    b) if no translation table is specified, the translation table;
                    only one source feature with /transgenic is allowed in an entry;
                    the /focus and /transgenic qualifiers are mutually exclusive in
                    an entry.

    Qualifier       /translation=
    Definition      automatically generated one-letter abbreviated amino acid
                    sequence derived from either the universal genetic code or the
                    table as specified in /transl_table and as determined by
                    exceptions in the /transl_except and /codon qualifiers
    Value format    IUPAC one-letter amino acid abbreviation, "X" is to be used
                    for AA exceptions.
    Example         /translation="MASTFPPWYRGCASTPSLKGLIMCTW"
    Comment         to be used with CDS feature only; this is a mandatory qualifier
                    in the CDS feature key except where /pseudo is shown;
                    see /transl_table for definition and location of genetic code
                    Tables.

    Qualifier       /transl_except=
    Definition      translational exception: single codon the translation of which
                    does not conform to genetic code defined by Organism and /codon=
    Value format    (pos:location,aa:<amino_acid>) where amino_acid is the
                    amino acid coded by the codon at the base_range position
    Example         /transl_except=(pos:213..215,aa:Trp)
                    /transl_except=(pos:1017,aa:TERM)
                    /transl_except=(pos:2000..2001,aa:TERM)
                    /transl_except=(pos:X22222:15..17,aa:Ala)
    Comment         if the amino acid is not on the restricted vocabulary list use
                    e.g., '/transl_except=(pos:213..215,aa:OTHER)' with
                    '/note="name of unusual amino acid"';
                    for modified amino-acid selenocysteine use three letter code
                    'Sec'  (one letter code 'U' in amino-acid sequence)
                    /transl_except=(pos:1002..1004,aa:Sec);
                    for partial termination codons where TAA stop codon is
                    completed by the addition of 3' A residues to the mRNA
                    either a single base_position or a base_range is used, e.g.
                    if partial stop codon is a single base:
                    /transl_except=(pos:1017,aa:TERM)
                    if partial stop codon consists of two bases:
                    /transl_except=(pos:2000..2001,aa:TERM) with
                    '/note='stop codon completed by the addition of 3' A residues
                    to the mRNA'.

    Qualifier       /transl_table=
    Definition      definition of genetic code table used if other than universal
                    genetic code table. Tables used are described in appendix V,
                    section 7.5.5.
    Value format    <integer; 1=universal table 1;2=non-universal table 2;...
    Example         /transl_table=4
    Comment         genetic code exceptions outside range of specified tables are
                    reported in /codon or /transl_except qualifiers.

    Qualifier       /trans_splicing
    Definition      indicates that exons from two RNA molecules are ligated in
                    intermolecular reaction to form mature RNA
    Value format    none
    Example         /trans_splicing
    Comment         should be used on features such as CDS, mRNA and other features
                    that are produced as a result of a trans-splicing event. This
                    qualifier should be used only when the splice event is indicated in
                    the "join" operator, eg join(complement(69611..69724),139856..140087)

    Qualifier       /variety=
    Definition      variety (= varietas, a formal Linnaean rank) of organism
                    from which sequence was derived.
    Value format    "text"
    Example         /variety="insularis"
    Comment         use the cultivar qualifier for cultivated plant
                    varieties, i.e., products of artificial selection;
                    varieties other than plant and fungal variatas should be
                    annotated via /note, e.g. /note="breed:Cukorova"

    7.4.2 Feature qualifiers - mapped to Feature keys

    The following is a list of available qualifiers mapped to the list of feature keys on which each qualifier is legal.
    QUALIFIER FEATURE KEY
    /allele  -10_signal
    /allele  -35_signal
    /allele  3'UTR
    /allele  5'UTR
    /allele  attenuator
    /allele  C_region
    /allele  CAAT_signal
    /allele  CDS
    /allele  conflict
    /allele  D_segment
    /allele  D-loop
    /allele  enhancer
    /allele  exon
    /allele  GC_signal
    /allele  gene
    /allele  iDNA
    /allele  intron
    /allele  J_segment
    /allele  LTR
    /allele  mat_peptide
    /allele  misc_binding
    /allele  misc_difference
    /allele  misc_feature
    /allele  misc_recomb
    /allele  misc_RNA
    /allele  misc_signal
    /allele  misc_structure
    /allele  modified_base
    /allele  mRNA
    /allele  N_region
    /allele  old_sequence
    /allele  operon
    /allele  oriT
    /allele  polyA_signal
    /allele  polyA_site
    /allele  precursor_RNA
    /allele  prim_transcript
    /allele  primer_bind
    /allele  promoter
    /allele  protein_bind
    /allele  RBS
    /allele  rep_origin
    /allele  repeat_region
    /allele  rRNA
    /allele  S_region
    /allele  sig_peptide
    /allele  stem_loop
    /allele  STS
    /allele  TATA_signal
    /allele  terminator
    /allele  transit_peptide
    /allele  tRNA
    /allele  unsure
    /allele  V_region
    /allele  V_segment
    /allele  variation
    /anticodon  tRNA
    /bio_material  source
    /bound_moiety  enhancer
    /bound_moiety  misc_binding
    /bound_moiety  oriT
    /bound_moiety  promoter
    /bound_moiety  protein_bind
    /cell_line  source
    /cell_type  source
    /chromosome  source
    /citation  -10_signal
    /citation  -35_signal
    /citation  3'UTR
    /citation  5'UTR
    /citation  attenuator
    /citation  C_region
    /citation  CAAT_signal
    /citation  CDS
    /citation  conflict
    /citation  D_segment
    /citation  D-loop
    /citation  enhancer
    /citation  exon
    /citation  GC_signal
    /citation  gene
    /citation  iDNA
    /citation  intron
    /citation  J_segment
    /citation  LTR
    /citation  mat_peptide
    /citation  misc_binding
    /citation  misc_difference
    /citation  misc_feature
    /citation  misc_recomb
    /citation  misc_RNA
    /citation  misc_signal
    /citation  misc_structure
    /citation  modified_base
    /citation  mRNA
    /citation  N_region
    /citation  old_sequence
    /citation  operon
    /citation  oriT
    /citation  polyA_signal
    /citation  polyA_site
    /citation  precursor_RNA
    /citation  prim_transcript
    /citation  primer_bind
    /citation  promoter
    /citation  protein_bind
    /citation  RBS
    /citation  rep_origin
    /citation  repeat_region
    /citation  rRNA
    /citation  S_region
    /citation  sig_peptide
    /citation  source
    /citation  stem_loop
    /citation  STS
    /citation  TATA_signal
    /citation  terminator
    /citation  transit_peptide
    /citation  tRNA
    /citation  unsure
    /citation  V_region
    /citation  V_segment
    /citation  variation
    /clone  misc_difference
    /clone  source
    /clone_lib  source
    /codon  CDS
    /codon_start  CDS
    /collected_by  source
    /collection_date  source
    /compare  conflict
    /compare  misc_difference
    /compare  old_sequence
    /compare  variation
    /compare  unsure
    /country  source
    /cultivar  source
    /culture_collection  source
    /db_xref  -10_signal
    /db_xref  -35_signal
    /db_xref  3'UTR
    /db_xref  5'UTR
    /db_xref  attenuator
    /db_xref  C_region
    /db_xref  CAAT_signal
    /db_xref  CDS
    /db_xref  conflict
    /db_xref  D_segment
    /db_xref  D-loop
    /db_xref  enhancer
    /db_xref  exon
    /db_xref  GC_signal
    /db_xref  gene
    /db_xref  iDNA
    /db_xref  intron
    /db_xref  J_segment
    /db_xref  LTR
    /db_xref  mat_peptide
    /db_xref  misc_binding
    /db_xref  misc_difference
    /db_xref  misc_feature
    /db_xref  misc_recomb
    /db_xref  misc_RNA
    /db_xref  misc_signal
    /db_xref  misc_structure
    /db_xref  modified_base
    /db_xref  mRNA
    /db_xref  N_region
    /db_xref  old_sequence
    /db_xref  operon
    /db_xref  oriT
    /db_xref  polyA_signal
    /db_xref  polyA_site
    /db_xref  precursor_RNA
    /db_xref  prim_transcript
    /db_xref  primer_bind
    /db_xref  promoter
    /db_xref  protein_bind
    /db_xref  RBS
    /db_xref  rep_origin
    /db_xref  repeat_region
    /db_xref  rRNA
    /db_xref  S_region
    /db_xref  sig_peptide
    /db_xref  source
    /db_xref  stem_loop
    /db_xref  STS
    /db_xref  TATA_signal
    /db_xref  terminator
    /db_xref  transit_peptide
    /db_xref  tRNA
    /db_xref  unsure
    /db_xref  V_region
    /db_xref  V_segment
    /db_xref  variation
    /dev_stage  source
    /direction  oriT
    /direction  rep_origin
    /EC_number  CDS
    /EC_number  exon
    /EC_number  mat_peptide
    /ecotype  source
    /environmental_sample  source
    /estimated_length  gap
    /exception  CDS
    /experiment  -10_signal
    /experiment  -35_signal
    /experiment  3'UTR
    /experiment  5'UTR
    /experiment  attenuator
    /experiment  C_region
    /experiment  CAAT_signal
    /experiment  CDS
    /experiment  conflict
    /experiment  D_segment
    /experiment  D-loop
    /experiment  enhancer
    /experiment  exon
    /experiment  GC_signal
    /experiment  gene
    /experiment  iDNA
    /experiment  intron
    /experiment  J_segment
    /experiment  LTR
    /experiment  mat_peptide
    /experiment  misc_binding
    /experiment  misc_difference
    /experiment  misc_feature
    /experiment  misc_recomb
    /experiment  misc_RNA
    /experiment  misc_signal
    /experiment  misc_structure
    /experiment  modified_base
    /experiment  mRNA
    /experiment  N_region
    /experiment  old_sequence
    /experiment  operon
    /experiment  oriT
    /experiment  polyA_signal
    /experiment  polyA_site
    /experiment  precursor_RNA
    /experiment  prim_transcript
    /experiment  primer_bind
    /experiment  promoter
    /experiment  protein_bind
    /experiment  RBS
    /experiment  rep_origin
    /experiment  repeat_region
    /experiment  rRNA
    /experiment  S_region
    /experiment  sig_peptide
    /experiment  stem_loop
    /experiment  STS
    /experiment  TATA_signal
    /experiment  terminator
    /experiment  transit_peptide
    /experiment  tRNA
    /experiment  unsure
    /experiment  V_region
    /experiment  V_segment
    /experiment  variation
    /focus  source
    /frequency  modified_base
    /frequency  source
    /frequency  variation
    /function  3'UTR
    /function  5'UTR
    /function  CDS
    /function  exon
    /function  gene
    /function  iDNA
    /function  intron
    /function  LTR
    /function  mat_peptide
    /function  misc_binding
    /function  misc_feature
    /function  misc_RNA
    /function  misc_signal
    /function  misc_structure
    /function  mRNA
    /function  operon
    /function  precursor_RNA
    /function  prim_transcript
    /function  promoter
    /function  protein_bind
    /function  repeat_region
    /function  rRNA
    /function  sig_peptide
    /function  stem_loop
    /function  transit_peptide
    /function  tRNA
    /gene  -10_signal
    /gene  -35_signal
    /gene  3'UTR
    /gene  5'UTR
    /gene  attenuator
    /gene  C_region
    /gene  CAAT_signal
    /gene  CDS
    /gene  conflict
    /gene  D_segment
    /gene  D-loop
    /gene  enhancer
    /gene  exon
    /gene  GC_signal
    /gene  gene
    /gene  iDNA
    /gene  intron
    /gene  J_segment
    /gene  LTR
    /gene  mat_peptide
    /gene  misc_binding
    /gene  misc_difference
    /gene  misc_feature
    /gene  misc_recomb
    /gene  misc_RNA
    /gene  misc_signal
    /gene  misc_structure
    /gene  modified_base
    /gene  mRNA
    /gene  N_region
    /gene  old_sequence
    /gene  oriT
    /gene  polyA_signal
    /gene  polyA_site
    /gene  precursor_RNA
    /gene  prim_transcript
    /gene  primer_bind
    /gene  promoter
    /gene  protein_bind
    /gene  RBS
    /gene  rep_origin
    /gene  repeat_region
    /gene  rRNA
    /gene  S_region
    /gene  sig_peptide
    /gene  stem_loop
    /gene  STS
    /gene  TATA_signal
    /gene  terminator
    /gene  transit_peptide
    /gene  tRNA
    /gene  unsure
    /gene  V_region
    /gene  V_segment
    /gene  variation
    /gene_synonym  -10_signal
    /gene_synonym  -35_signal
    /gene_synonym  3'UTR
    /gene_synonym  5'UTR
    /gene_synonym  attenuator
    /gene_synonym  C_region
    /gene_synonym  CAAT_signal
    /gene_synonym  CDS
    /gene_synonym  conflict
    /gene_synonym  D_segment
    /gene_synonym  D-loop
    /gene_synonym  enhancer
    /gene_synonym  exon
    /gene_synonym  GC_signal
    /gene_synonym  gene
    /gene_synonym  iDNA
    /gene_synonym  intron
    /gene_synonym  J_segment
    /gene_synonym  LTR
    /gene_synonym  mat_peptide
    /gene_synonym  misc_binding
    /gene_synonym  misc_difference
    /gene_synonym  misc_feature
    /gene_synonym  misc_recomb
    /gene_synonym  misc_RNA
    /gene_synonym  misc_signal
    /gene_synonym  misc_structure
    /gene_synonym  modified_base
    /gene_synonym  mRNA
    /gene_synonym  N_region
    /gene_synonym  old_sequence
    /gene_synonym  oriT
    /gene_synonym  polyA_signal
    /gene_synonym  polyA_site
    /gene_synonym  precursor_RNA
    /gene_synonym  prim_transcript
    /gene_synonym  primer_bind
    /gene_synonym  promoter
    /gene_synonym  protein_bind
    /gene_synonym  RBS
    /gene_synonym  rep_origin
    /gene_synonym  repeat_region
    /gene_synonym  rRNA
    /gene_synonym  S_region
    /gene_synonym  sig_peptide
    /gene_synonym  stem_loop
    /gene_synonym  STS
    /gene_synonym  TATA_signal
    /gene_synonym  terminator
    /gene_synonym  transit_peptide
    /gene_synonym  tRNA
    /gene_synonym  unsure
    /gene_synonym  V_region
    /gene_synonym  V_segment
    /gene_synonym  variation
    /germline  source
    /haplotype  source
    /host  source
    /identified_by  source
    /inference  -10_signal
    /inference  -35_signal
    /inference  3'UTR
    /inference  5'UTR
    /inference  attenuator
    /inference  C_region
    /inference  CAAT_signal
    /inference  CDS
    /inference  conflict
    /inference  D_segment
    /inference  D-loop
    /inference  enhancer
    /inference  exon
    /inference  GC_signal
    /inference  gene
    /inference  iDNA
    /inference  intron
    /inference  J_segment
    /inference  LTR
    /inference  mat_peptide
    /inference  misc_binding
    /inference  misc_difference
    /inference  misc_feature
    /inference  misc_recomb
    /inference  misc_RNA
    /inference  misc_signal
    /inference  misc_structure
    /inference  modified_base
    /inference  mRNA
    /inference  N_region
    /inference  old_sequence
    /inference  operon
    /inference  oriT
    /inference  polyA_signal
    /inference  polyA_site
    /inference  precursor_RNA
    /inference  prim_transcript
    /inference  primer_bind
    /inference  promoter
    /inference  protein_bind
    /inference  RBS
    /inference  rep_origin
    /inference  repeat_region
    /inference  rRNA
    /inference  S_region
    /inference  sig_peptide
    /inference  stem_loop
    /inference  STS
    /inference  TATA_signal
    /inference  terminator
    /inference  transit_peptide
    /inference  tRNA
    /inference  unsure
    /inference  V_region
    /inference  V_segment
    /inference  variation
    /isolate  source
    /isolation_source  source
    /lab_host  source
    /label  -10_signal
    /label  -35_signal
    /label  3'UTR
    /label  5'UTR
    /label  attenuator
    /label  C_region
    /label  CAAT_signal
    /label  CDS
    /label  conflict
    /label  D_segment
    /label  D-loop
    /label  enhancer
    /label  exon
    /label  GC_signal
    /label  gene
    /label  iDNA
    /label  intron
    /label  J_segment
    /label  LTR
    /label  mat_peptide
    /label  misc_binding
    /label  misc_difference
    /label  misc_feature
    /label  misc_recomb
    /label  misc_RNA
    /label  misc_signal
    /label  misc_structure
    /label  modified_base
    /label  mRNA
    /label  N_region
    /label  old_sequence
    /label  operon
    /label  oriT
    /label  polyA_signal
    /label  polyA_site
    /label  precursor_RNA
    /label  prim_transcript
    /label  primer_bind
    /label  promoter
    /label  protein_bind
    /label  RBS
    /label  rep_origin
    /label  repeat_region
    /label  rRNA
    /label  S_region
    /label  sig_peptide
    /label  source
    /label  stem_loop
    /label  STS
    /label  TATA_signal
    /label  terminator
    /label  transit_peptide
    /label  tRNA
    /label  unsure
    /label  V_region
    /label  V_segment
    /label  variation
    /lat_lon  source
    /locus_tag  -10_signal
    /locus_tag  -35_signal
    /locus_tag  3'UTR
    /locus_tag  5'UTR
    /locus_tag  attenuator
    /locus_tag  C_region
    /locus_tag  CAAT_signal
    /locus_tag  CDS
    /locus_tag  conflict
    /locus_tag  D_segment
    /locus_tag  D-loop
    /locus_tag  enhancer
    /locus_tag  exon
    /locus_tag  GC_signal
    /locus_tag  gene
    /locus_tag  iDNA
    /locus_tag  intron
    /locus_tag  J_segment
    /locus_tag  LTR
    /locus_tag  mat_peptide
    /locus_tag  misc_binding
    /locus_tag  misc_difference
    /locus_tag  misc_feature
    /locus_tag  misc_recomb
    /locus_tag  misc_RNA
    /locus_tag  misc_signal
    /locus_tag  misc_structure
    /locus_tag  modified_base
    /locus_tag  mRNA
    /locus_tag  N_region
    /locus_tag  old_sequence
    /locus_tag  oriT
    /locus_tag  polyA_signal
    /locus_tag  polyA_site
    /locus_tag  precursor_RNA
    /locus_tag  prim_transcript
    /locus_tag  primer_bind
    /locus_tag  promoter
    /locus_tag  protein_bind
    /locus_tag  RBS
    /locus_tag  rep_origin
    /locus_tag  repeat_region
    /locus_tag  rRNA
    /locus_tag  S_region
    /locus_tag  sig_peptide
    /locus_tag  stem_loop
    /locus_tag  STS
    /locus_tag  TATA_signal
    /locus_tag  terminator
    /locus_tag  transit_peptide
    /locus_tag  tRNA
    /locus_tag  unsure
    /locus_tag  V_region
    /locus_tag  V_segment
    /locus_tag  variation
    /macronuclear  source
    /map  -10_signal
    /map  -35_signal
    /map  3'UTR
    /map  5'UTR
    /map  attenuator
    /map  C_region
    /map  CAAT_signal
    /map  CDS
    /map  conflict
    /map  D_segment
    /map  D-loop
    /map  enhancer
    /map  exon
    /map  GC_signal
    /map  gap
    /map  gene
    /map  iDNA
    /map  intron
    /map  J_segment
    /map  LTR
    /map  mat_peptide
    /map  misc_binding
    /map  misc_difference
    /map  misc_feature
    /map  misc_recomb
    /map  misc_RNA
    /map  misc_signal
    /map  misc_structure
    /map  modified_base
    /map  mRNA
    /map  N_region
    /map  old_sequence
    /map  operon
    /map  oriT
    /map  polyA_signal
    /map  polyA_site
    /map  precursor_RNA
    /map  prim_transcript
    /map  primer_bind
    /map  promoter
    /map  protein_bind
    /map  RBS
    /map  rep_origin
    /map  repeat_region
    /map  rRNA
    /map  S_region
    /map  sig_peptide
    /map  source
    /map  stem_loop
    /map  STS
    /map  TATA_signal
    /map  terminator
    /map  transit_peptide
    /map  tRNA
    /map  unsure
    /map  V_region
    /map  V_segment
    /map  variation
    /mating_type  source
    /mobile_element  repeat_region
    /mod_base  modified_base
    /mol_type  source
    /ncRNA_class  ncRNA
    /note  -10_signal
    /note  -35_signal
    /note  3'UTR
    /note  5'UTR
    /note  attenuator
    /note  C_region
    /note  CAAT_signal
    /note  CDS
    /note  conflict
    /note  D_segment
    /note  D-loop
    /note  enhancer
    /note  exon
    /note  GC_signal
    /note  gap
    /note  gene
    /note  iDNA
    /note  intron
    /note  J_segment
    /note  LTR
    /note  mat_peptide
    /note  misc_binding
    /note  misc_difference
    /note  misc_feature
    /note  misc_recomb
    /note  misc_RNA
    /note  misc_signal
    /note  misc_structure
    /note  modified_base
    /note  mRNA
    /note  N_region
    /note  old_sequence
    /note  operon
    /note  oriT
    /note  polyA_signal
    /note  polyA_site
    /note  precursor_RNA
    /note  prim_transcript
    /note  primer_bind
    /note  promoter
    /note  protein_bind
    /note  RBS
    /note  rep_origin
    /note  repeat_region
    /note  rRNA
    /note  S_region
    /note  sig_peptide
    /note  source
    /note  stem_loop
    /note  STS
    /note  TATA_signal
    /note  terminator
    /note  transit_peptide
    /note  tRNA
    /note  unsure
    /note  V_region
    /note  V_segment
    /note  variation
    /number  CDS
    /number  exon
    /number  iDNA
    /number  intron
    /number  misc_feature
    /old_locus_tag  -10_signal
    /old_locus_tag  -35_signal
    /old_locus_tag  3'UTR
    /old_locus_tag  5'UTR
    /old_locus_tag  attenuator
    /old_locus_tag  C_region
    /old_locus_tag  CAAT_signal
    /old_locus_tag  CDS
    /old_locus_tag  conflict
    /old_locus_tag  D_segment
    /old_locus_tag  D-loop
    /old_locus_tag  enhancer
    /old_locus_tag  exon
    /old_locus_tag  GC_signal
    /old_locus_tag  gene
    /old_locus_tag  iDNA
    /old_locus_tag  intron
    /old_locus_tag  J_segment
    /old_locus_tag  LTR
    /old_locus_tag  mat_peptide
    /old_locus_tag  misc_binding
    /old_locus_tag  misc_difference
    /old_locus_tag  misc_feature
    /old_locus_tag  misc_recomb
    /old_locus_tag  misc_RNA
    /old_locus_tag  misc_signal
    /old_locus_tag  misc_structure
    /old_locus_tag  modified_base
    /old_locus_tag  mRNA
    /old_locus_tag  N_region
    /old_locus_tag  old_sequence
    /old_locus_tag  oriT
    /old_locus_tag  polyA_signal
    /old_locus_tag  polyA_site
    /old_locus_tag  precursor_RNA
    /old_locus_tag  prim_transcript
    /old_locus_tag  primer_bind
    /old_locus_tag  promoter
    /old_locus_tag  protein_bind
    /old_locus_tag  RBS
    /old_locus_tag  rep_origin
    /old_locus_tag  repeat_region
    /old_locus_tag  rRNA
    /old_locus_tag  S_region
    /old_locus_tag  sig_peptide
    /old_locus_tag  stem_loop
    /old_locus_tag  STS
    /old_locus_tag  TATA_signal
    /old_locus_tag  terminator
    /old_locus_tag  transit_peptide
    /old_locus_tag  tRNA
    /old_locus_tag  unsure
    /old_locus_tag  V_region
    /old_locus_tag  V_segment
    /old_locus_tag  variation
    /operon  -10_signal
    /operon  -35_signal
    /operon  attenuator
    /operon  CDS
    /operon  gene
    /operon  misc_RNA
    /operon  misc_signal
    /operon  mRNA
    /operon  operon
    /operon  precursor_RNA
    /operon  prim_transcript
    /operon  promoter
    /operon  protein_bind
    /operon  rRNA
    /operon  stem_loop
    /operon  terminator
    /organelle  source
    /organism  source
    /PCR_conditions  primer_bind
    /PCR_primers  source
    /phenotype  attenuator
    /phenotype  gene
    /phenotype  misc_difference
    /phenotype  misc_feature
    /phenotype  misc_signal
    /phenotype  operon
    /phenotype  promoter
    /phenotype  variation
    /plasmid  source
    /pop_variant  source
    /product  C_region
    /product  CDS
    /product  D_segment
    /product  exon
    /product  gene
    /product  J_segment
    /product  mat_peptide
    /product  misc_feature
    /product  misc_RNA
    /product  mRNA
    /product  N_region
    /product  precursor_RNA
    /product  rRNA
    /product  S_region
    /product  sig_peptide
    /product  transit_peptide
    /product  tRNA
    /product  V_region
    /product  V_segment
    /product  variation
    /protein_id  CDS
    /proviral  source
    /pseudo  C_region
    /pseudo  CDS
    /pseudo  D_segment
    /pseudo  exon
    /pseudo  gene
    /pseudo  intron
    /pseudo  J_segment
    /pseudo  mat_peptide
    /pseudo  misc_feature
    /pseudo  misc_RNA
    /pseudo  mRNA
    /pseudo  N_region
    /pseudo  operon
    /pseudo  promoter
    /pseudo  rRNA
    /pseudo  S_region
    /pseudo  sig_peptide
    /pseudo  transit_peptide
    /pseudo  tRNA
    /pseudo  V_region
    /pseudo  V_segment
    /rearranged  source
    /replace  conflict
    /replace  misc_difference
    /replace  old_sequence
    /replace  unsure
    /replace  variation
    /ribosomal_slippage  CDS
    /rpt_family  oriT
    /rpt_family  repeat_region
    /rpt_type  oriT
    /rpt_type  repeat_region
    /rpt_unit_range  oriT
    /rpt_unit_range  repeat_region
    /rpt_unit_seq  oriT
    /rpt_unit_seq  repeat_region
    /satellite  repeat_region
    /segment  source
    /serotype  source
    /serovar  source
    /sex  source
    /specimen_voucher  source
    /standard_name  -10_signal
    /standard_name  -35_signal
    /standard_name  3'UTR
    /standard_name  5'UTR
    /standard_name  C_region
    /standard_name  CDS
    /standard_name  D_segment
    /standard_name  enhancer
    /standard_name  exon
    /standard_name  gene
    /standard_name  iDNA
    /standard_name  intron
    /standard_name  J_segment
    /standard_name  LTR
    /standard_name  mat_peptide
    /standard_name  misc_difference
    /standard_name  misc_feature
    /standard_name  misc_recomb
    /standard_name  misc_RNA
    /standard_name  misc_signal
    /standard_name  misc_structure
    /standard_name  mRNA
    /standard_name  N_region
    /standard_name  operon
    /standard_name  oriT
    /standard_name  precursor_RNA
    /standard_name  prim_transcript
    /standard_name  primer_bind
    /standard_name  promoter
    /standard_name  protein_bind
    /standard_name  RBS
    /standard_name  rep_origin
    /standard_name  repeat_region
    /standard_name  rRNA
    /standard_name  S_region
    /standard_name  sig_peptide
    /standard_name  stem_loop
    /standard_name  STS
    /standard_name  terminator
    /standard_name  transit_peptide
    /standard_name  tRNA
    /standard_name  V_region
    /standard_name  V_segment
    /standard_name  variation
    /strain  source
    /sub_clone  source
    /sub_species  source
    /sub_strain  source
    /tag_peptide  tmRNA
    /tissue_lib  source
    /tissue_type  source
    /transgenic  source
    /transl_except  CDS
    /transl_table  CDS
    /translation  CDS
    /trans_splicing  CDS
    /trans_splicing  gene
    /trans_splicing  misc_RNA
    /trans_splicing  mRNA
    /trans_splicing  precursor_RNA
    /trans_splicing  tRNA
    /trans_splicing  3'UTR
    /trans_splicing  5'UTR
    /variety  source

    7.5 Appendix V: Controlled vocabularies

    This appendix contains information on the restricted vocabulary fields used in
    the Feature Table. The information contained in this appendix is subject to
    change, please contact the database staff for the most recent information
    concerning controlled vocabularies. This appendix is organized as follows:

    Authority       The organization with authority to define the vocabulary
    Reference       Publications of (or about) the vocabulary
    Contact         Name of database staff responsible for maintaining
                    the database copy of the vocabulary
    Scope           Feature Table qualifiers which take members of this vocabulary
                    as values
    Listing         A listing of the current vocabulary with definitions or
                    explanations
    This appendix includes reference lists for the following controlled vocabulary
    fields:
    - Nucleotide base codes (IUPAC)
    - Modified base abbreviations
    - Amino acid abbreviations
    - Modified and unusual Amino Acids
    - Genetic Code Tables
    - Country Names

    7.5.1 Nucleotide base codes (IUPAC)

    Authority       Nomenclature Committee of the International Union of
                    Biochemistry
    Reference       Cornish-Bowden, A.  Nucl Acid Res 13, 3021-3030 (1985)
    Contact         EMBL-EBI
    Scope           Location descriptors

    Listing

            Symbol  Meaning
            ------  -------

            a       a; adenine
            c       c; cytosine
            g       g; guanine
            t       t; thymine in DNA; uracil in RNA
            m       a or c
            r       a or g
            w       a or t
            s       c or g
            y       c or t
            k       g or t
            v       a or c or g; not t
            h       a or c or t; not g
            d       a or g or t; not c
            b       c or g or t; not a
            n       a or c or g or t

    7.5.2 Modified base abbreviations

    Authority       Sprinzl, M. and Gauss, D.H.
    Reference       Sprinzl, M. and Gauss, D.H.  Nucl Acid Res  10, r1 (1982).
                    (note that in Cornish_Bowden, A.  Nucl Acid Res  13, 3021-3030
                    (1985) the IUPAC-IUB declined to recommend a set of
                    abbreviations for modified nucleotides)
    Contact         NCBI
    Scope           /mod_base

            Abbreviation    Modified base description
            ------------    -------------------------
            ac4c            4-acetylcytidine
            chm5u           5-(carboxyhydroxylmethyl)uridine
            cm              2'-O-methylcytidine
            cmnm5s2u        5-carboxymethylaminomethyl-2-thiouridine
            cmnm5u          5-carboxymethylaminomethyluridine
            d               dihydrouridine
            fm              2'-O-methylpseudouridine
            gal q           beta,D-galactosylqueosine
            gm              2'-O-methylguanosine
            i               inosine
            i6a             N6-isopentenyladenosine
            m1a             1-methyladenosine
            m1f             1-methylpseudouridine
            m1g             1-methylguanosine
            m1i             1-methylinosine
            m22g            2,2-dimethylguanosine
            m2a             2-methyladenosine
            m2g             2-methylguanosine
            m3c             3-methylcytidine
            m5c             5-methylcytidine
            m6a             N6-methyladenosine
            m7g             7-methylguanosine
            mam5u           5-methylaminomethyluridine
            mam5s2u         5-methoxyaminomethyl-2-thiouridine
            man q           beta,D-mannosylqueosine
            mcm5s2u         5-methoxycarbonylmethyl-2-thiouridine
            mcm5u           5-methoxycarbonylmethyluridine
            mo5u            5-methoxyuridine
            ms2i6a          2-methylthio-N6-isopentenyladenosine
            ms2t6a          N-((9-beta-D-ribofuranosyl-2-methyltiopurine-6-yl)car
                            bamoyl)threonine
            mt6a            N-((9-beta-D-ribofuranosylpurine-6-yl)N-methyl-carbam
                            oyl)threonine
            mv              uridine-5-oxyacetic acid-methylester
            o5u             uridine-5-oxyacetic acid (v)
            osyw            wybutoxosine
            p               pseudouridine
            q               queosine
            s2c             2-thiocytidine
            s2t             5-methyl-2-thiouridine
            s2u             2-thiouridine
            s4u             4-thiouridine
            t               5-methyluridine
            t6a             N-((9-beta-D-ribofuranosylpurine-6-yl)carbamoyl)threo
                            nine
            tm              2'-O-methyl-5-methyluridine
            um              2'-O-methyluridine
            yw              wybutosine
            x               3-(3-amino-3-carboxypropyl)uridine, (acp3)u
            OTHER           (requires /note= qualifier)

    7.5.3 Amino acid abbreviations

    Authority       IUPAC-IUB Joint Commission on Biochemical Nomenclature.
    Reference       IUPAC-IUB Joint Commission on Biochemical Nomenclature.
                    Nomenclature   and    Symbolism   for   Amino   Acids   and
                    Peptides.
                    Eur. J. Biochem. 138:9-37(1984).
                    IUPAC-IUBMB JCBN Newsletter, 1999
                    http://www.chem.qmul.ac.uk/iubmb/newsletter/1999/item3.html
    Scope           /anticodon, /codon, /transl_except
    Contact         EMBL-EBI

    Listing (note that the abbreviations are legal values for amino acids, not the full names)
            Abbreviation    Amino acid name
            ------------    ---------------

            Ala     A       Alanine
            Arg     R       Arginine
            Asn     N       Asparagine
            Asp     D       Aspartic acid (Aspartate)
            Cys     C       Cysteine
            Gln     Q       Glutamine
            Glu     E       Glutamic acid (Glutamate)
            Gly     G       Glycine
            His     H       Histidine
            Ile     I       Isoleucine
            Leu     L       Leucine
            Lys     K       Lysine
            Met     M       Methionine
            Phe     F       Phenylalanine
            Pro     P       Proline
            Pyl     O       Pyrrolysine
            Ser     S       Serine
            Sec     U       Selenocysteine
            Thr     T       Threonine
            Trp     W       Tryptophan
            Tyr     Y       Tyrosine
            Val     V       Valine
            Asx     B       Aspartic acid or Asparagine
            Glx     Z       Glutamine or Glutamic acid.
            Xaa     X       Any amino acid.
            Xle     J       Leucine or Isoleucine
            TERM            termination codon

    7.5.4 Modified and unusual Amino Acids
            Abbreviation    Amino acid
            ------------    ---------

            Aad             2-Aminoadipic acid
            bAad            3-Aminoadipic acid
            bAla            beta-Alanine, beta-Aminoproprionic acid
            Abu             2-Aminobutyric acid
            4Abu            4-Aminobutyric acid, piperidinic acid
            Acp             6-Aminocaproic acid
            Ahe             2-Aminoheptanoic acid
            Aib             2-Aminoisobutyric acid
            bAib            3-Aminoisobutyric acid
            Apm             2-Aminopimelic acid
            Dbu             2,4-Diaminobutyric acid
            Des             Desmosine
            Dpm             2,2'-Diaminopimelic acid
            Dpr             2,3-Diaminoproprionic acid
            EtGly           N-Ethylglycine
            EtAsn           N-Ethylasparagine
            Hyl             Hydroxylysine
            aHyl            allo-Hydroxylysine
            3Hyp            3-Hydroxyproline
            4Hyp            4-Hydroxyproline
            Ide             Isodesmosine
            aIle            allo-Isoleucine
            MeGly           N-Methylglycine, sarcosine
            MeIle           N-Methylisoleucine
            MeLys           6-N-Methyllysine
            MeVal           N-Methylvaline
            Nva             Norvaline
            Nle             Norleucine
            Orn             Ornithine
            OTHER           (requires /note=)

    7.5.5 Genetic Code Tables

    Authority      International Nucleotide Sequence Database Collaboration
    Contact        NCBI
    Scope          /transl_table qualifier
    URL            http://www.ncbi.nlm.nih.gov/Taxonomy/Utils/wprintgc.cgi?mode=c

      Genetic Code [1]
      Standard Code (transl_table=1)

        AAs  = FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = ---M---------------M---------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [2]
      Vertebrate Mitochondrial Code (transl_table=2)

        AAs  = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSS**VVVVAAAADDEEGGGG
      Starts = --------------------------------MMMM---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [3]
      Yeast Mitochondrial Code (transl_table=3)

        AAs  = FFLLSSSSYY**CCWWTTTTPPPPHHQQRRRRIIMMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = ----------------------------------MM----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [4]
      Mold, Protozoan, Coelenterate Mitochondrial Code & Mycoplasma/Spiroplasma
      Code (transl_table=4)

        AAs  = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = --MM---------------M------------MMMM---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [5]
      Invertebrate Mitochondrial Code (transl_table=5)

        AAs  = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSSSVVVVAAAADDEEGGGG
      Starts = ---M----------------------------MMMM---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [6]
      Ciliate, Dasycladacean and Hexamita Nuclear Code (transl_table=6)

        AAs  = FFLLSSSSYYQQCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = -----------------------------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [9]
      Echinoderm and Flatworm Mitochondrial Code (transl_table=9)

        AAs  = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG
      Starts = -----------------------------------M---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [10]
      Euplotid Nuclear Code (transl_table=10)

        AAs  = FFLLSSSSYY**CCCWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = -----------------------------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [11]
      Bacterial and Plant Plastid Code (transl_table=11)

        AAs  = FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = ---M---------------M------------MMMM---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [12]
      Alternative Yeast Nuclear Code (transl_table=12)

        AAs  = FFLLSSSSYY**CC*WLLLSPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = -------------------M---------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [13]
      Ascidian Mitochondrial Code (transl_table=13)

        AAs  = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSGGVVVVAAAADDEEGGGG
      Starts = ---M------------------------------MM---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [14]
      Alternative Flatworm Mitochondrial Code (transl_table=14)

        AAs  = FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG
      Starts = -----------------------------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [15]
      Blepharisma Nuclear Code (transl_table=15)

        AAs  = FFLLSSSSYY*QCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = -----------------------------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [16]
      Chlorophycean Mitochondrial Code (transl_table=16)

        AAs  = FFLLSSSSYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = -----------------------------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [21]
      Trematode Mitochondrial Code (transl_table=21)

        AAs  = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNNKSSSSVVVVAAAADDEEGGGG
      Starts = -----------------------------------M---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [22]
      Scenedesmus obliquus mitochondrial

        AAs  = FFLLSS*SYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = -----------------------------------M----------------------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

      Genetic Code [23]
      Thraustochytrium Mitochondrial Code (transl_table=23)

        AAs  = FF*LSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG
      Starts = --------------------------------M--M---------------M------------
      Base1  = TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG
      Base2  = TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG
      Base3  = TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG

    7.5.6 Country Names

    Authority       International Nucleotide Sequence Database Collaboration
    Contact         INSDC member databases
    Scope           /country qualifier
    URL             http://www.insdc.org/page.php?page=country

    Feature Table Definition
    Version 8  Oct, 2008